EC Pharmacology And Toxicology

Research Article Volume 12 Issue 9 - 2024

Production of Secondary Metabolites Using Lacto Bacillus and its Antibacterial Studies against Multidrug Resistant Bacteria

P Sagadevan1*, R Kannan1, M Raghunath1, M Nagarajan1, R Subashkumar2, N Sribala1 and P Jenifer Brintha1

1PG Department of Biotechnology, KSG College of Arts and Science Coimbatore, Tamilnadu, India
2PG Research Department of Biotechnology Sri Ramakrishna College of Arts and Science Coimbatore, Tamilnadu, India
*Corresponding Author: P Sagadevan, Assistant Professor, PG Department of Biotechnology, KSG College of Arts and Science Coimbatore, Tamilnadu, India.
Received: August 19, 2024; Published: September 06, 2023



In the current study, the surface protein was disengaged from Lactobacillus spp. utilizing altered medium. The extracellular protein was removed, and the protein content was assessed. The compound was further, to some degree, cleansed utilizing dialysis, segment chromatography, and MRS medium. The protein was additionally portrayed utilizing UV-VV is studies, and the pinnacle was seen at 286 nm. The FTIR was additionally done, and the different utilitarian gatherings were likewise examined to affirm the amide and nitriles gatherings. The antibacterial movement was completed utilizing the removed protein, and the medication was stacked with the protein to expand the proficiency of the protein. The bacterial surface layers are translucent varieties of self-collecting, proteinaceous subunits called S-layer proteins (slps), with atomic masses going from 40 to 200 kDa. Our discoveries additionally demonstrate that the cell surface proteins add to their expanded bond to the refined cells and serious prohibition of microbes.

 Keywords: FTIR; Lactobacillus spp.; MRS Medium

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P Sagadevan., et al. “Production of Secondary Metabolites Using Lacto Bacillus and its Antibacterial Studies against Multidrug Resistant Bacteria” ”. EC Pharmacology and Toxicology  12.9 (2024): 01-14.