EC Nutrition

Research Article Volume 14 Issue 4 - 2019

New Bulgarian Food Supplement in the Treatment and Prevention of Obesity

Stella Schekerdjiiska1, Tеodora Handjieva-Darlenska2*, Nikolay Georgiev1 and Alexander Oscar3

1Natstim, Sofia, Bulgaria

2Department of Pharmacology and Toxicology, Medical University, Sofia, Bulgaria

3Department of Ophthalmology, Medical University, Sofia, Bulgaria

*Corresponding Author: Tеodora Handjieva-Darlenska, Department of Pharmacology and Toxicology, Medical University, Sofia, Bulgaria.
Received: September 06, 2018; Published: March 27, 2019



The new Bulgarian food supplement consist of the alginic acid salts and antioxidative complex. Our aim is to examine the effect of alginates on the weight loss and BMI in patients with obesity. After six week treatment with alginates significant decrease of the body weight and BMI (p 0,01) is established in comparison to the control group. Alginates assures a mechanical satiety. The food supplement possesses a good temperance and lack of side effects. Our results demonstrate that Bulgarian food supplement alginates inhibits the development of the obesity in male Wistar rats. In addition, alginates has the capacity to reduce the hyperglycemia and hypertriglyceridemia. Moreover, the product did not present side effects in rats.

keywords: Obesity; Bulgarian Food Supplement; BMI

  • Yumuk V., et al. “Obesity Management Task Force of the European Association for the Study of Obesity, European Guidelines for Obesity Management in Adults”. Obesity Facts6 (2015): 402-424.
  • Handjieva Darlenska T., et al. “The alginates in the treatment of obesity/clinical and experimental study”. Obesity Facts1 (2018): 329.
  • Handjieva-Darlenska T and Boyadjieva N. “The effects of alginates on the appetite and weight in obese rats”. Obesity Facts1 (2014): 72.
  • Kimura Y., et al. “Effects of soluble sodium alginate on cholesterol excretion and glucose tolerance in rats”. Journal of Ethnopharmacology1 (1996): 47-54.
  • Odunsi ST., et al. “Effect of alginate on satiation, appetite, gastric function, and selected gut satiety hormones in overweight and obesity”. Obesity8 (2010): 1579-1584.
  • Handjieva-Darlenska T and Boyadjieva N. “Obesity: Pharmacotherapy and Pharmacogenetics”. Sofia, Simelpress (2007): 289-305.
  • Paxman JR., et al. “Daily ingestion of alginate reduces energy intake in free-living subjects”. Appetite3 (2008): 713-719.
  • Handjieva-Darlenska T. “Clinical pharmacological study of the effect of alginates in the treatment of obesity”. GP News, 8-2325 (2014).
  • Handjiev Sv., et al. “The new Bulgarian supplement Algigracil-Instant in the treatment of obesity”. Transport Medicine 24 (2002): 23- 24.
  • Birketvedt GS., et al. “Experiences with three different fiber supplements in weight reduction”. Medical Science Monitor 1 (2005): PI5-PI8.
  • Pelkman CL., et al. “Novel calcium-gelled, alginate-pectin beverage reduced energy intake in nondieting overweight and obese women: interactions with dietary restraint status”. American Journal of Clinical Nutrition6 (2007): 1595-1602.
  • Paxman JR., et al. “Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study”. Nutrition Research 8 (2008): 501-505.
  • Solah VA., et al. “Differences in satiety effects of alginate- and whey protein-based foods”. Appetite3 (2010): 485-491.

    • Tеodora Handjieva-Darlenska., et al. “Healthy Diet and Association with an Increasing Trend towards Foods with Probiotics”. EC Nutrition  14.4 (2019): 344-348.

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