Opinion Volume 21 Issue 2 - 2026

Interplay Between Metabolic Reprogramming and Immunity: A Key Role of Superfood as Sources of Vitamins and Antioxidants in Prevention of Different Pathologies and for Healthy Aging and Focus on NAD+ Prospectives

Maria Luigia Pallotta*

Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, Campobasso, Italy

*Corresponding Author: Maria Luigia Pallotta, Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, Campobasso, Italy.
Received: January 27, 2026; Published: February 05, 2026



Immune cell activation, differentiation, and effector functions are governed by tightly coordinated metabolic reprogramming involving a network of interconnected biochemical pathways. Glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway (PPP) constitute the core metabolic axes sustaining bioenergetic demands, generating biosynthetic intermediates, and preserving redox balance during immune responses.

Maria Luigia Pallotta. “Interplay Between Metabolic Reprogramming and Immunity: A Key Role of Superfood as Sources of Vitamins and Antioxidants in Prevention of Different Pathologies and for Healthy Aging and Focus on NAD+ Prospectives”. EC Nutrition  21.2 (2026): 01-03.