EC Nutrition

Editorial Volume 18 Issue 6 - 2023

Integrated Antioxidant Defence Network in Animals

Peter F Surai1-7*

1Vitagene and Health Research Centre, Bristol, UK
2Department of Microbiology and Biochemistry, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
3Department of Animal Nutrition, Faculty of Agricultural and Environmental Sciences, Szent Istvan University, Hungary
4Russian Academy of Sciences, Moscow, Russia
4Saint-Petersburg State Academy of Veterinary Medicine, St. Petersburg, Russia
6Sumy National Agrarian University, Sumy, Ukraine
7Odessa National Academy of Food Technologies, Odessa, Ukraine
*Corresponding Author: Peter F Surai, Vitagene and Health Research Centre, Bristol, UK.
Received: May 25, 2023; Published: May 31, 2023



For the last 3 decades it has become clear that over-production of free radicals leading to oxidative stress and redox disbalance is involved in the development of different human/animal diseases at various stages of their development. Therefore, during evolution an integrated antioxidant defence network was developed to provide effective protection of biological molecules against damaging effects of reactive oxygen and nitrogen species (RONS) and toxic products of their metabolism. Previously we suggested vitamin E and coenzyme Q to be called “head quarter” of the antioxidant system, while carotenoids, comprising a group of pigments accounting for more than 1000 compounds to be called “communicating services” of the antioxidant defence.

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  8. Surai PF and Kochish II. “Nutritional modulation of the antioxidant capacities in poultry: the case of selenium”. Poultry Science 98 (2019): 4231-4239.
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  10. Surai PF., et al. “Taurine in poultry nutrition”. Animal Feed Science and Technology 260 (2020): 114339.
  11. Surai PF., et al. “Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models”. Antioxidants 10 (2021): 1876.
  12. Surai PF. “Antioxidant action of carnitine: molecular mechanisms and practical applications”. EC Veterinary Science 1 (2015): 66-84.
  13. Surai PF. “Carnitine enigma: from antioxidant action to vitagene regulation. Part 2. Transcription factors and practical applications”. Journal of Veterinary Science and Medicine 3 (2015): 17.
  14. Surai PF. “Polyphenol compounds in the chicken/animal diet: from the past to the future”. Journal of Animal Physiology and Animal Nutrition 98 (2014): 19-31.
  15. Surai PF. “Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives”. Antioxidants 4 (2015): 204-247.

Peter F Surai. "Integrated Antioxidant Defence Network in Animals". EC Nutrition 18.6 (2023): 18-20.

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