EC Nutrition

Research Article Volume 19 Issue 4 - 2024

Effect of Breadfruit (Treculia africana) Leaf Extract on Some Hormones in Male Wistar Rats

Nnodim Johnkennedy*, Williams Comfort Ekom and Johnkennedy Promise Amarachi

Department of Medical Laboratory Science, Faculty of Health Science, Imo State University, Owerri, Nigeria

*Corresponding Author: Nnodim Johnkennedy, Department of Medical Laboratory Science, Faculty of Health Science, Imo State University, Owerri, Nigeria.
Received: March 14, 2024; Published: March 21, 2024

This study aims to investigate how breadfruit leaf extract affects the hormone profile: (Testosterone, follicle stimulating hormone (FSH), luteinizing hormone (LH) and prolactin) of male albino rats. Twenty (20) male albino wistar rats (200 - 220g final body weight) were randomly assigned into 2 groups of 10 rats each. Group I served as control while group II was administered 400 mg/kg body weight of breadfruit leaf extract for 28 days. The results showed that the levels of testosterone, FSH and LH were significantly increased in the group that received 400 mg/dl extract of breadfruit leaves when compared to control at p < 0.05. While prolactin was significantly decreased when compared with the control at p < 0.05. This result implies that the consumption of breadfruit leaf extract could enhance reproductive functions in male albino Wistar rats and is likely to increase fertility.

 Keywords: Breadfruit; Testosterone; Follicle Stimulating Hormone (FSH); Luteinizing Hormone (LH); Prolactin; Male Albino Rats

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Nnodim Johnkennedy. “Effect of Breadfruit (Treculia africana) Leaf Extract on Some Hormones in Male Wistar Rats”. EC Nutrition  19.4 (2024): 01-05.