Review Article Volume 14 Issue 9 - 2025

The Importance of the Pneumonia Guiding Concept in the Fight against Sepsis

I Klepikov*

MD, Professor, Retired, Renton, WA, USA

*Corresponding Author: I Klepikov, MD, Professor, Retired, Renton, WA, USA.
Received: June 23, 2025; Published: August 12, 2025



Sepsis (SS) is currently one of the leading problems of global health. Being a complication of various inflammatory diseases, SS is diagnosed in more than half of cases as a consequence of severe acute inflammation of the lung tissue, often at the very beginning of the disease. Despite such an obvious connection with pneumonia, SS has recently been considered and studied as a separate syndrome. The experience of previous studies and clinical trials indicates that a radical change in conceptual ideas about the uniqueness of the pathogenesis of inflammation in the lungs and the priority of pathogenetic approaches in justifying its treatment opens up opportunities for the prevention of such complications.

 Keywords: Sepsis; Acute Pneumonia; Pathogenesis; Pulmonogenic Shock; Pseudosepsis

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I Klepikov. “The Importance of the Pneumonia Guiding Concept in the Fight against Sepsis”. EC Pulmonology and Respiratory Medicine  14.9 (2025): 01-11.