Objectives: We propose to conduct a study on the evolutionary profile of patients with silicosis received in the Pneumology Department of the Tenkodogo Regional Hospital.

Materials and Methods: This was a prospective cohort study to follow all cases of silicosis recruited in the CHRT pneumology department over the 3-year period from 01 May 2020 to 30 April 2023.

Results: A total of 151 patients were included in our study. The mean age was 29.66 ± 7.11 (15 - 50 years old). The management of patients was carried out on an outpatient basis in 81 or 53.64% and in hospitalization in 70 patients (46.36%). A worsening of the clinical condition of patients was observed in 66 patients (43.71%) with a death rate of 29.80%. The survival rate in our study was 70.10% at 6 months, 66.10% at 01 year and 59.70% at 2 years. An exposure duration of more than 10 years was statistically associated with death (p < 0.001) as was impairment of general condition and cardiac impact.

Conclusion: The evolution of patients with silicosis in our context remains worrying in view of the severe respiratory disability and high mortality rate.

Keywords: Silicosis; Evolution; CHRT

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