Research Article Volume 14 Issue 12 - 2025

Changing Characteristics of Rheumatoid Arthritis during the Last Third of the 20th Century - A Postmortem Clinicopathologic Study of 237 Autopsy Patients

Miklós Bély1* and Ágnes Apáthy2

1Department of Pathology, Hospital of the Order of the Brothers of Saint John of God in Budapest, Hungary

2Department of Rheumatology, St. Margaret Clinic, Budapest, Hungary

*Corresponding Author: Miklós Bély, Department of Pathology, Hospital of the Order of the Brothers of Saint John of God in Budapest, Hungary.
Received: October 21, 2025; Published: November 17, 2025



The characteristics of rheumatoid arthritis (RA) can change over time.

This has happened during the last third of the 20th century and noted by the changes of incidence and mortality of autoimmune vasculitis, AA amyloidosis, acute bacterial septic infection, and purulent arthritis.

New drugs, a consequent therapeutic strategy and patient awareness play an important role in improving the patient's life expectancy and quality of life, but RA cannot be cured today despite our therapeutic efforts and the introduction of new drugs.

 Keywords: Changing Characteristics; Rheumatoid Arthritis; Autoimmune Vasculitis; AA Amyloidosis; Acute Bacterial Septic Infection; Purulent Arthritis

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Miklós Bély and Ágnes Apáthy. “Changing Characteristics of Rheumatoid Arthritis during the Last Third of the 20th Century - A Postmortem Clinicopathologic Study of 237 Autopsy Patients”. EC Pulmonology and Respiratory Medicine  14.12 (2025): 01-16.