EC Pulmonology and Respiratory Medicine

Case Study Volume 13 Issue 10 - 2024

A Case of Perinatal Tuberculosis with Adverse Reaction to Antituberculous Drugs and Hypercalcemia: An Underestimated Enemy

Luque Graciela F1, Bisero Elsa D1*, Lombardero Lorena A1, Giusti Silvana1, Dehesa R2, Giménez EA1 and Melillo Karina C1

1Professor Alejandro Posadas National Hospital, Maternal and Child Department, Pediatrics Division, Childhood Pulmonology Service, El Palomar, Provincia de Buenos Aires, Argentina

2Pediatric Intensive Care Service, El Palomar, Provincia de Buenos Aires, Argentina

*Corresponding Author: Bisero Elsa D, Professor Alejandro Posadas National Hospital, Maternal and Child Department, Pediatrics Division, Childhood Pulmonology Service, El Palomar, Provincia de Buenos Aires, Argentina.
Received: August 14, 2024; Published: October 08, 2024



The clinical presentation of perinatal tuberculosis (PTB) is highly variable. It can range from an asymptomatic condition to nonspecific symptoms such as lethargy, fever, feeding difficulties, poor weight gain, respiratory distress, hepatosplenomegaly, lymphadenopathy, abdominal distension with ascites, or a clinical picture resembling "neonatal sepsis”. Its approach involves using tools to establish differential diagnoses with other infectious diseases and the immediate study of household contacts. Complications, sequelae, and high mortality rates are often recorded, depending on the form of presentation and the time elapsed until diagnosis and treatment, making it a true medical challenge. The objective of this report is to present a case of PTB with multisystem failure, hepatic adverse reaction to anti-TB drugs (ADR) and hypercalcemia.

 Keywords: Tuberculosis; Perinatal Tuberculosis; Hypercalcemia; Disseminated Tuberculosis; Adverse Reactions to Antituberculous Drugs

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Bisero Elsa D., et al. "A Case of Perinatal Tuberculosis with Adverse Reaction to Antituberculous Drugs and Hypercalcemia: An Underestimated Enemy". EC Pulmonology and Respiratory Medicine  13.10 (2024): 01-08.