EC Paediatrics

Case Report Volume 13 Issue 12 - 2024

Syndrome of Paroxysmal Sympathetic Hyperactivity as a Variant of the Complicated Course of the Postoperative Period in a 9-Month-Old Child with Neurosurgical Pathology. Clinical Observation

Savvina IA1,2,3*, Gurskaya VI1, Blinov SA3,4 and Alexandrovich Yu S4

1Almazov National Medical Research Center, St. Petersburg, Russia
2North-West State Medical University Named After I.I. Mechnikov, St. Petersburg, Russia
3Children's Region Clinical Hospital, St. Petersburg, Russia
4St. Petersburg State Pediatric Medical University, St. Petersburg, Russia

*Corresponding Author: Savvina IA, Almazov National Medical Research Center, St. Petersburg, Russia.
Received: October 29, 2024; Published: November 13, 2024




The paper describes a clinical observation with a complicated course of the postoperative period in the form of the development of paroxysmal sympathetic hyperactivity (PSH) syndrome in the infant after acute cerebral injury caused by neurosurgical intervention to remove the formation of the oculomotor nerve on the left. The issues of diagnosis and intensive therapy of PSH syndrome are considered.

 Keywords: Neurosurgery; Paediatric Patients; Acute Cerebral Injury; Paroxysmal Sympathetic Hyperactivity Syndrome

  1. Baguley IJ., et al. “Paroxysmal sympathetic hyperactivity after acquired brain injury: consensus on conceptual definition, nomenclature, and diagnostic criteria”. Journal of Neurotrauma17 (2014): 1515-1520.
  2. Meyfroidt G., et al. “Paroxysmal sympathetic hyperactivity: the storm after acute brain injury”. Lancet Neurology9 (2017): 721-729.
  3. Podell JE., et al. “Paroxysmal sympathetic hyperactivity after traumatic brain injury: a case-control study”. Critical Care Medicine 10 (2021): e989-e1000.
  4. Godoy DA., et al. “Paroxysmal sympathetic hyperactivity: An entity to keep in mind”. Medicina Intensiva 1 (2019): 35-43.
  5. Thomas A and Greenwald BD. “Paroxysmal sympathetic hyperactivity and clinical considerations for patients with acquired brain injuries: a narrative review”. American Journal of Physical Medicine and Rehabilitation 1 (2019): 65-72.
  6. Louraoui SM., et al. “Paroxysmal sympathetic hyperactivity after traumatic brain injury: What is important to know?” Cureus5 (2022): e24693.
  7. van Eijck MM., et al. “The use of the PSH-AM in patients with diffuse axonal injury and autonomic dysregulation: A cohort study and review”. Journal of Critical Care 49 (2019): 110-117.
  8. Hinson HE., et al. “Neuroanatomical basis of paroxysmal sympathetic hyperactivity: a diffusion tensor imaging analysis”. Brain Injury4 (2015): 455-461.
  9. Pozzi M., et al. “Clinical scales for paroxysmal sympathetic hyperactivity in pediatric patients”. Journal of Neurotrauma 22 (2014): 1897-1898.
  10. Rabinstein AA and Benarroch EE. “Treatment of paroxysmal sympathetic hyperactivity”. Current Treatment Options in Neurology 2 (2008): 151-157.
  11. Savvina IA., et al. “Cerebral vasospasm: Mechanisms, Pathomorphology, Diagnostics, Treatment”. In: Cerebrovascular Diseases - elucidating Key Principles/ Ed. by Dr. Patricia Bozzetto Ambrosi. IntechOpen, London (2022): 138.
  12. Savvina IA and Petrova AO. “The treatment of acute stroke/ischemic stroke”. Ed. by Pratap Sanchetee. London: IntechOpen (2021): 85-102.
  13. Savvina IA., et al. “Management of pediatric severe traumatic brain injury: what are news?” EC Anaesthesia10 (2020): 1-14.

Savvina IA., et al. "Syndrome of Paroxysmal Sympathetic Hyperactivity as a Variant of the Complicated Course of the Postoperative Period in a 9-Month-Old Child with Neurosurgical Pathology. Clinical Observation". EC Paediatrics 13.12 (2024): 01-09.

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