EC Paediatrics

Opsoclonus-myoclonus-ataxia is a clinical syndrome which may be of paraneoplastic, infectious, post-infectious, post-vaccination or idiopathic origin. We report the case of a 23-month-old infant hospitalized for gait disorders with abnormal eye movements. Examination revealed an irritable infant with cerebellar ataxia and multidirectional nystagmus. Brain MRI was normal. The thoracoabdominal CT scan showed an adrenal neuroblastoma. The treatment was symptomatic by corticosteroid therapy and etiological by surgery and chemotherapy. Neuroblastoma remains the most common etiology of opsomyoclonic syndrome in pediatrics.

Keywords: Neuroblastoma; Opsoclonus-Myoclonus; Paraneoplastic Syndrome

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