EC Paediatrics

Case Report Volume 12 Issue 6 - 2023

Neonatal Listeriosis Resistant to Ampicillin: A Case Report

Wejdan Ibrahim Alhusaini1*, Riham Ibrahim Fallatah2 and Alaa Al-Juaid3

1General Pediatric Demonstrator at University of Jeddah, Pediatric Saudi Board, KAAUH, Faculty of Medicine, Pediatric Infectious Disease Fellow at Prince Sultan Military Medical City and NGHA, Jeddah, KSA
2Pediatric Infectious Disease Consultant at MCSH - Jeddah, Pediatric Saudi Board, KAAUH, Faculty of Medicine, Pediatric Infectious Disease Fellow at KFSH and RS and NGHA, Jeddah, KSA
3Supervisor Consultant, Pediatric Infectious Disease Consultant-King Abdulaziz Medical City, Program Director of the Pediatric Infectious Disease, Assistant Professor of Pediatrics Infectious Disease at king Saud bin Abdulaziz University for Health Sciences, KSA

*Corresponding Author: Wejdan Ibrahim Alhusaini, General Pediatric Demonstrator at University of Jeddah, Pediatric Saudi Board, KAAUH, Faculty of Medicine, Pediatric Infectious Disease Fellow at Prince Sultan Military Medical City and NGHA, Jeddah, KSA.
Received: October 17, 2022; Published: May 04, 2023



Background: Perinatal listerial infection is the most common clinical syndrome caused by Listeria monocytogenes and includes abortion, still birth, neonatal sepsis, and meningitis. Listeriosis is caused by the foodborne pathogen Listeria monocytogenes. It can present as a maternal-neonatal infection.

Case Presentation: A female newborn with birthweight of 750 grams was delivered vaginally at 25 weeks of gestation. Both the 1- and 5-minute Apgar scores were 4. Respiratory distress and bradycardia necessitated the insertion of an endotracheal tube and the initiation of ventilation assistance. Newborn infection was resistant to ampicillin and was then treated with vancomycin and gentamycin. However, the infant's condition suddenly deteriorated the next day, and the baby ultimately passed away due to cyanosis and bradycardia.

Conclusion: Listeria in newborn is rare, yet some cases has been addressed in the literature. Early detection and treatment might lead to good outcomes. However, resistant strains are emerging making the management more difficult and worsen the outcome. Mothers’ are advised to avoid foodborne infection with Listeria during pregnancy as this severely affect the pregnancy outcome as reported in the current case.

Keywords: Neonatal Listeriosis; Resistant to Ampicillin

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Wejdan Ibrahim Alhusaini., et al. Neonatal Listeriosis Resistant to Ampicillin: A Case Report. EC Paediatrics 12.6 (2023): 45-50.