EC Paediatrics

Background: Global developmental delay (GDD) is defined as a significant delay in one or more of the developmental domains [1,2]. The causes for GDD vary extensively making systematic evaluation crucial. Although in some cases a definite diagnosis may not be reached by imaging, MRI plays a significant role in assessing patients with developmental delay [2,3].

Aims and Objectives: This study aims to analyze the spectrum of MRI findings in pediatric patients with developmental delay.

Materials and Methods: A retrospective, observational study was conducted over five years four months (April 2018-August 2023) on 128 pediatric patients referred for MRI with a diagnosis of GDD. The MRI findings were evaluated and classified into eight categories.

Results: Of the 128 cases, 37 (28.9%) had normal MRI findings while 91 (71%) presented abnormalities. Out of the 91 abnormal cases, the most common abnormalities were delayed myelination (28.6%) and neurovascular abnormalities (27.5%). There was no significant difference in the prevalence of abnormal MRI when classified by presentation as isolated GDD and GDD with other associated conditions.

Conclusion and Key Message:

• The causes of GDD are many and varied and the treatment of these patients is complex and multidimensional.
• MRI serves as a valuable tool for evaluate patients with the clinical diagnosis of developmental delay, aiding in the diagnosis, prognostication, treatment and parental counseling [11].

Keywords: MRI-Magnetic Resonance Imaging; GDD-Global Developmental Delay; VR Spaces-Virchow Robin Spaces; PVL-Periventricular Leukomalacia; HIE-Hypoxic Ischemic Encephalopathy

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