EC Paediatrics

Review Article Volume 14 Issue 1 - 2025

High-Flow Nasal Cannula Oxygen Therapy in Infants and Children Versus Other Non-Invasive Ventilation: A Review of Current Knowledge

Mariam Mahmoud Hassan Mahmoud Elmakkawy1*, Zurina Binti Zainudin1, Safwat Hassan Gad2, Melissa Anne Nunis1, Mohd Fahmi Bin Ellias1 and Khairoon Nisa Mohamed Nashrudin1

1Department of Paediatrics, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia
 2Department of Paediatrics, Faculty of Medicine, Asian Institute of Medicine, Science and Technology (AIMST University), Kedah, Malaysia

*Corresponding Author: Mariam Mahmoud Hassan Mahmoud Elmakkawy, Department of Paediatrics, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia.
Received: December 23, 2024; Published: December 30, 2024




Respiratory distress is the leading cause of hospitalisation in paediatric intensive care units. Non-invasive ventilation can be delivered via continuous positive airway pressure (CPAP), bilevel positive airway pressure (BiPAP) or high-flow nasal cannula (HFNC). HFNC protocols are based only on manufacturers’ studies, with positive nasopharyngeal pressure as the primary endpoint. These protocols recommend the use of humidified air to prevent irritation of the airway mucosa. HFNC therapy may be better tolerated than traditional modes of non-invasive support, such CPAP and BiPAP in part owing to its smaller nasal prong interface allowing activities like breastfeeding with greater ease.

 Keywords: Paediatric Intensive Care; Continuous Positive Airway Pressure; High-Flow Nasal Cannula; Non-Invasive Ventilation; Preterm Infants

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Mariam Mahmoud Hassan Mahmoud Elmakkawy., et al. "High-Flow Nasal Cannula Oxygen Therapy in Infants and Children Versus Other Non-Invasive Ventilation: A Review of Current Knowledge". EC Paediatrics 14.1 (2025): 01-05.

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