EC Paediatrics

Research Article Volume 13 Issue 6 - 2024

Frequency of Successful Outcome of Intramuscular Midazolam for the Treatment of Status Epilepticus in Children

Aiman Islam1, Afsheen Batool Raza2*, Muhammad Khalid Masood3 and Nadia Nawaz4

1The Children’s Hospital and University of Child Health Sciences, Lahore, Pakistan
 2Associate Professor of Pediatrics, The Children’s Hospital and University of Child Health Sciences, Lahore, Pakistan
 3Professor of Paediatrics, University of Child Health Sciences, Lahore, Pakistan
 4Senior Registrar, Children’s Hospital, Lahore, Pakistan

*Corresponding Author: Afsheen Batool Raza, Associate Professor of Pediatrics, The Children’s Hospital and University of Child Health Sciences, Lahore, Pakistan.
Received: May 06, 2024; Published: May 27, 2024




Aims and Objectives:

  1. To find out the frequency of successful outcome of intramuscular midazolam for the treatment of status epilepticus in children.
  2. To compare successful outcome with respect to previous history of convulsions.

Patients and Methods: This cross sectional study was conducted in department of Paediatrics Children’s Hospital Lahore. Non-probability consecutive sampling technique was used and a total of 370 patients meeting inclusion criteria were included in this study. After taking an informed consent, patient’s contact information and demographic data was obtained. IM midazolam was used with a dose of 0.3 mg/kg and was injected into the left quadriceps muscle and final outcome was noted.

Results: The mean age of cases was 7.68 ± 4.10 years with minimum age as 4 months and maximum 14 years. One hundred (27%) cases had past history of seizures. A total of 350 (94.6%) cases had successful outcome while in 20 (5.4%) of the cases the outcome was not successful.

Conclusion: In this study, IM midazolam is found successful for the treatment of status epilepticus in children. Thus, this mode of treatment can be utilized in treating such cases to gain maximum therapeutic effectiveness.

 Keywords: Status Epilepticus; Seizures; Benzodiazepines; Midazolam; Diazepam

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Afsheen Batool Raza., et al. "Frequency of Successful Outcome of Intramuscular Midazolam for the Treatment of Status Epilepticus in Children". EC Paediatrics 13.6 (2024): 01-06.

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