EC Paediatrics

Case Report Volume 14 Issue 10 - 2025

Femoral Pain in a Child Revealing Monofocal Langerhans Cell Histiocytosis: A Radiologist Challenge

Fatima Chait1*, Nourrelhouda Bahlouli1, Nidal Mrani Alaoui2, Fadoua Boughaleb2,  2, El Medhi Tarik2, Naoual el Ansari3, Najat Lamalmi4, Nazik Allali1, Siham El Haddad1 and Latifa Chat1

1Pediatric Radiology Department, Pediatric Teaching Hospital, Mohammed V University, Rabat, Morocco

2Pediatric Surgery Department, Pediatric Teaching Hospital, Mohammed V University, Rabat, Morocco

3Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco

4Anatomo-Pathology Department, Pediatric Teaching Hospital, Mohammed V University, Rabat, Morocco

*Corresponding Author: Fatima Chait, Pediatric Radiology Department, Pediatric Teaching Hospital, Mohammed V University, Rabat, Morocco.
Received: June 26, 2025; Published: September 19, 2025




Langerhans cell histiocytosis is a rare disease characterized by the proliferation of CD1a-positive immature dendritic cells, which can affect both sexes at any age. The lesions can be multifocal or localized. The organs most frequently affected are bone, lung, skin and endocrine glands.

Imaging plays a crucial role in the diagnosis and management of patients with Langerhans cell histiocytosis.

We report an observation of monofocal langerhansian histiocytosis in a 2-year-old girl involving the left femur. Histological examination revealed Langerhansian histiocytosis. The evolution was favourable after systemic chemotherapy.

 Keywords: Femoral Pain; Monofocal Histiocytosis; Imaging

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Fatima Chait., et al. “Femoral Pain in a Child Revealing Monofocal Langerhans Cell Histiocytosis: A Radiologist Challenge”. EC Paediatrics  14.10 (2025): 01-06.

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