Research Article Volume 15 Issue 1 - 2026

Efficacy of Central Line Bundle Compliance on Central Line Associated Blood Stream Infections (CLABSI) among Neonatal Patients of An Intensive Care Unit

Dinesh Ari* and Faisal Al-Zidgali

Sheikh Shakhbout Medical City, UAE

*Corresponding Author: Dinesh Ari, Sheikh Shakhbout Medical City, UAE.
Received: December 16, 2025; Published: January 05, 2026



Background and Aim: Nosocomial infections pose an important threat to patient safety and recovery. The present study aimed to evaluate the effect of central line bundle compliance on central line associated blood stream infections in neonatal intensive care units.

Methods: The six components of bundle compliance were Hand hygiene, adherence to aseptic techniques including sterile gloves, gown, surgical cap and mask, preparing skin with 2% Chlorhexidine in 70% alcohol, optimal catheter site selection (Internal jugular or subclavian vein), standardized tubing change and daily review of catheter necessity. Compliance of CL bundle and CLABSIs were measured in the neonatal ICU from January 2019 to December 2019.

Results: A total of 2 CLABSI were reported of the patients who completed CL bundles. The major causes of central line infection included contamination, suboptimal environment of care, improper documentation and evaluation of central venous catheter dressing integrity, issues with equipment and suppliers and lack of knowledge.

Conclusion: This study provides evidence that CL bundle compliance is essential in preventing CLABSI in intensive care units. This could largely avoid neonatal deaths associated with infections.

 Keywords: Central Venous Catheters; Catheter-Related Infections; Intensive Avoid; Neonatal; Central Line Bundle

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Dinesh Ari and Faisal Al-Zidgali. “Efficacy of Central Line Bundle Compliance on Central Line Associated Blood Stream Infections (CLABSI) among Neonatal Patients of An Intensive Care Unit”. EC Paediatrics  15.1 (2026): 01-06.