EC Paediatrics

Case Report Volume 14 Issue 6 - 2025

A Low Dose of Ibuprofen May Result in Considerable Gastrointestinal Bleeding in Paediatrics

Shayna Swaine1, Fuad Kara'een2, Ahmed Osman3*, Imad Boles4, Lalani Heva4, Manivannan Kandasamy4, Wimal Nettikumara4, Salah Mansy4, Arjola Krymi3, Andrean Peters3, Haytham Ibrahim3, Yossra Elayouty3 and Enes Coskun5

1Foundation Programme Year 1 Doctor, ESHT, United Kingdom
2Training Paediatrics Doctor, Department of Paediatrics, ESHT, United Kingdom
3Speciality Paediatrics Doctor, Department of Paediatrics, ESHT, United Kingdom
4Consultant of Paediatrics, Department of Paediatrics, ESHT, United Kingdom
5Clinical Fellow, Paediatric Gastroenterology, King’s College Hospital, London, United Kingdom

*Corresponding Author: Ahmed Osman, Speciality Paediatrics Doctor, Department of Paediatrics, ESHT, United Kingdom.
Received: April 24, 2025; Published: May 26, 2025



Upper gastrointestinal (GI) bleeding includes blood loss within the GI system, proximal to the ligament of Treitz, which includes the oesophagus, stomach, and duodenum. GI bleeding can occur due to multiple causes and can be a presenting symptom for paediatrics patients. Patients may present with specific symptoms of haematemesis (vomiting blood), melaena (tarry, black stools), and coffee-ground type vomitus. Patients may also have associated systemic symptoms such as abdominal pain, fatigue, pallor, shortness of breath, light-headedness, and dizziness. Common causes of upper GI bleeding include gastric and duodenal ulcers, esophagitis, gastritis, bleeding disorders, coagulopathies, and necrotizing enterocolitis. Management is often a multifactorial approach, including fluid resuscitation, blood transfusion, endoscopy, drug intervention, and/or surgical intervention. If there is a large amount of blood loss, emergency resuscitation and stabilization of the patient may be necessary. Non-steroidal anti-inflammatory drug (NSAID)-induced haematemesis is a notable cause of upper GI bleeding in paediatrics patients. In our case, we have observed a severe case of upper GI bleeding, likely associated with NSAID administration.

 Keywords: Low Dose; Ibuprofen; Gastrointestinal Bleeding; Paediatrics

Ahmed Osman., et al. "A Low Dose of Ibuprofen May Result in Considerable Gastrointestinal Bleeding in Paediatrics". EC Paediatrics 14.6 (2025): 01-05.