Retrospective Qualitative Study Volume 16 Issue 4 - 2025

The New Age Gladiator: ACL Allograft Reconstruction Has Low Revision Rates in Patients Over 40

Branden Brooks1*, Larry Martin Jr2 and Lisa K Cannada3

1University of California, Davis School of Medicine, Nth Dimensions, USA

2Department of Orthopedics Sports Medicine, Novant Health, Charlotte, North Carolina, USA

3Department of Orthopedics Trauma Surgery, Novant Health, Charlotte, North Carolina, USA

*Corresponding Author: Branden Brooks, University of California, Davis School of Medicine, Nth Dimensions, Sacramento, California, USA.
Received: June 19, 2025; Published: July 25, 2025



Introduction: The aging population are participating in more athletic and physically demanding activities longer and later in life. Advances in medicine have helped to facilitate these activities as well as treating injuries that come along with such activities. Anterior cruciate ligament (ACL) injuries have always been a devastating injury, but with better surgical procedures and rehabilitation they are merely season ending and not career ending. The debate over the best graft for ACL reconstructions has been ongoing for years and there are numerous studies supporting all types. This study aims to report allografts are an equally viable and effective option for ACL reconstruction in patients over 40 years of age with no difference in re-rupture rates.

Methods: This is a retrospective qualitative study using medical records for patients who underwent an ACL reconstruction by a single provider at Novant Health Orthopedics and Sports Medicine from 2018 - 2022 (n = 104). Of those ACL reconstructions, patients over 40 who had allografts were identified (n = 30). All allografts were bone patellar tendon bone (BPTB) grafts with pre-shaped bone blocks measuring 10mm in diameter and 95 - 100 mm in length provided by Musculoskeletal Transplant Foundation (MTF) biologics. The same sterilization allowash technique was performed on each allograft. All patients followed a specific post operative protocol including physical therapy and weight bearing in a brace immediately post operatively with crutches.

Medical records were reviewed, and patients were contacted via telephone for follow-up information. Data interpreted included demographics, mechanism of injury, pre and post op ROM, pre and post op function, return to sport, complications, re-rupture and subjective instability. The data collected was all categorical and results collated.

Results: See figure 1.

Conclusion: With no patients with a re-rupture, our study provides insight into supporting our hypothesis that patients over 40 years of age can return to physical activity and receive long term benefits from ACL reconstruction using allografts.

 Keywords: Anterior Cruciate Ligament; ACL; Arthroscopy; Joints; Sports Medicine; Allograft

  1. Kaplan Y and Witvrouw E. “When is it safe to return to sport after ACL reconstruction? reviewing the criteria”. Sports Health4 (2019): 301-305.
  2. Kraeutler MJ., et al. “Bone-patellar tendon-bone autograft versus allograft in outcomes of anterior cruciate ligament reconstruction: a meta-analysis of 5182 patients”. The American Journal of Sports Medicine10 (2013): 2439-2448.
  3. Engler ID., et al. “Revision rates after primary allograft ACL reconstruction by allograft tissue type in older patients”. Orthopaedic Journal of Sports Medicine 9 (2023): 23259671231198538.
  4. Kaeding CC., et al. “Allograft versus autograft anterior cruciate ligament reconstruction: predictors of failure from a MOON prospective longitudinal cohort”. Sports Health1 (2011): 73-81.
  5. Hulet C., et al. “The use of allograft tendons in primary ACL reconstruction”. Knee Surgery, Sports Traumatology, Arthroscopy 6 (2019): 1754-1770.
  6. Belk JW., et al. “Autograft demonstrates superior outcomes for revision anterior cruciate ligament reconstruction when compared with allograft: a systematic review”. The American Journal of Sports Medicine3 (2023): 859-867.
  7. McGuire DA and Hendricks SD. “Allograft tissue in ACL reconstruction”. Sports Medicine and Arthroscopy Review 4 (2009): 224-233.
  8. Wright RW., et al. “Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the multicenter ACL revision study (MARS) cohort”. The American Journal of Sports Medicine10 (2014): 2301-2310.
  9. Kaeding CC., et al. “Risk factors and predictors of subsequent ACL injury in either knee after ACL reconstruction: prospective analysis of 2488 primary ACL reconstructions from the MOON cohort”. The American Journal of Sports Medicine7 (2015): 1583-1590.

Branden Brooks., et al. “The New Age Gladiator: ACL Allograft Reconstruction Has Low Revision Rates in Patients Over 40”. EC Orthopaedics  16.4 (2025): 01-04.