EC Orthopaedics

Schizophrenia is a biopsychosocial model that evolves insidiously in childhood by combining programmed genetic aspects, modu- lated psychosocial aspects and situational conditions of the specific human ecology. The aim of the study was to determine the as- sociations of risk factors for schizophrenia in order to integrate them into the personal history of a single case according to its total singularity. Using mixed method approaches, we integrated the data from the experiment through a sample of 101 schizophrenic subjects into the clinical and singular experience of the subjective life of a single case suffering from schizophrenia from the age of 13 to the age of 39, that is to say 26 years of continuous psychic suffering, bio-medico-psychological care at the University Psychiatric Center of Kinshasa, DR Congo. The results plead in favor of an early and primary care which would imply the learning of positive and not negligent parenthood with the accompaniment of the youth to minimize the risk factors before their irreversible pathological constellation in other words: (the construction of the “mental blindness by a psychic glaucoma”). These associations and single cases constitute a preliminary phase of studies in the approach of early and primary prevention, aiming to promote protective factors and prevent by minimizing the risk factors of the constellation and triggering of schizophrenia spectrum disorders in youth.

Keywords: Associations; Schizophrenia; Risk Factors; Genetics; Social Environment; Holistic Care, Learning, Early Prevention

1. Guelfi JD. “Mini DSM-4 TR: Diagnostic criteria”. Elsevier Masson (2004).
2. Dahdouh GA., et al. “Consanguinity, schizophrenia and bipolar disorders”. Annales Médico-Psychologiques 4 (2013): 246-250.
3. Cassou B., et al. “Genetics and schizophrenia: reappraisal of a consensus”. La Psychiatrie de l'enfant1 (1980): 87-201.
4. Baron Cohen S. “Mental blindness, an essay on autism and theory of mind”. Grenoble: PUG Bronché (1998).
5. Divignau K. “For a semantic approach to oral and written language disorders. The APPROX project ANAE Rev”. Neuropsychologie des Apprentissages 9 (2008): 65-70.
6. Coulibaly SP., et al. “Factors associated with mental disorders in the psychiatry department of the Centre hospitalier universitaire du Point G in Mali”. Le Mali Medical1 (2021): 52-57.
7. “Mental health action plan, 2013-2020”. World Health Organization (2020).
8. Campion D. “Genetics of schizophrenia, the supplement. Risk factors”. Med Sc, Paris: Pub Med,6-7 (2016): 556-557.
9. Chaumette B., et al. “Genetics and epigenetics of schizophrenia and psychoses”. Biologie Aujourd'hui 1 (2017): 69-82.
10. Brunelin J. “Vulnerability to schizophrenia: clinical, cognitive and neurophysiological approach of the positive dimension”. Doctoral dissertation Lyon 1. Lyon (2017).
11. Peyre H. “Epidemiology of children's cognitive development during the preschool period”. Sorbonne neuroscience thesis. Paris: UPMC (2017).
12. Marc Richard. “Attentional abilities in neglected children aged 5 to 12 years”. Master's thesis in psychology. Quebec City: Université de Trois Rivières (2003).
13. Ngalamulume D. “Understanding post-traumatic stress disorder in DR Congo”. Moldavia: Ed. des Universités Européennes, EUE (2021).
14. Berger FF. "The symbolic adventure. Clinique du sujet et du lien social contemporain”. Doctoral thesis in clinical psychology. FLASH University of Nice. France (2013).
15. Senninger JL. “Stressful life events and the criminality of schizophrenics”. Encéphale22 (1996): 49-50.
16. Senninger JL. “Schizophrenia: Current research and perspectives”. Encéphale22 (1996): 1-118.
17. Ethier L., et al. “Prévenir la négligence parentale”. Revue Québécoise de Psychologie3 (1994): 67-86.
18. Auxémery Y. “Post-traumatic stress disorder as a consequence of the interaction between an individual genetic susceptibility, a traumatic event and a social context”. Encephale5 (2012): 373-380.
19. Ionescu J. “Psychopathology of schizophrenia” (1997).
20. Auxémery Y. “Posttraumatic psychotic disorders: a pathophysiological model of schizophrenia”. Elsevier Masson 169.3 (2011): 155.
21. Birot E. “The object relationship in the parents of schizophrenics”. Psychiatrie de l'Enfant2 (1984): 433-521.
22. Creswell JW and Plano Clark VL. “Disigning and conducting mixed methods research (2^nd edition)”. Thousand OAKS: Sage Publications (2011).
23. Creswell JW. “A concise introduction to mixed methods research”. Thousand OAKS: Sage Publications (2014).
24. Plano Clark VL., et al. “Mixing quantitative and qualitative approaches. An introduction to emergent mixed methods research”. In SN Hoss Biber and Leavy (Eds. Handbook of emergent methods. New York Guilford Press (2010): 363-383.
25. American Psychiatric Association Diagnostic and statistical of mental disorders (DSM- 5 2013). Types of schizophrenias.
26. American Psychiatric Association Diagnostic and statistical of mental disorders (DSM- 4 1994). Washington DC.
27. De Baurepaire. “Schizophrenia and other psychoses in DSM-5”. The Psychiatrist's Letter 2 (2014): 62-63.