EC Neurology

The dramatic difference in human quality of life, health, and lifespan may depend not on the pool of inherited genes but their relative expression. Specific genes turned on to express related functions with others suppressed under the control mechanisms grouped under the term "epigenetics." The polyphenolic compound 6-Shogaol demonstrated significant potential in improving the clinical condition of MDS patients and is discussed as a possible epigenetic compound.

 Keywords: Shogaols; 6-Shogaol; MDS; BOS; ASXL 1 Gene; Epigenetics

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