EC Neurology

Metastases extra neural stemming from are a rare progression of glioblastoma, with an incidence of 0.4 - 0.5% of all glioblastoma cases. The locations can be extraneural, such as leptomeninges and dural venous sinuses, extraneural and extracranial, such as solid organs and lymph nodes [5], yet in this study, we report the case of a patient previously diagnosed with glioblastoma presenting extramedullary dural metastases. The lesson learned from this case is to look for early craniospinal metastasis in GBM patient [6].

 Keywords: Glioblastoma; Dural; Metastasis; Extraneural; CNS

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2. Michael Lettau., et al. “Dural metastases of a glioblastoma”. Clinical Neuroradiology4 (2013): 323-325.
3. HG Terheggen and W Müller. “Extracerebrospinal metastases in glioblastoma”. European Journal of Pediatrics2 (1977): 155-164.
4. Abhishek Ray., et al. “Extracranial metastasis of glioblastoma: Three illustrative cases and current review of the molecular pathology and management strategies”. Molecular and Clinical Oncology3 (2015): 479-486.
5. Zhewei Anthony. “Metastatic glioblastoma”. Radiopaedia (2023).
6. Subhas K Konar., et al. “Early dural metastasis from a case of glioblastoma with primitive neuroectodermal differentiation: A case report and literature review”. Journal of Clinical Neuroscience 35 (2017): 78-81.
7. Lauren L Hintenlang., et al. “Treatment of a glioblastoma multiforme dural metastasis with stereotactic radiosurgery: A case report and select review of the literature”. Journal of Clinical Neuroscience 48 (2018): 118-121.