EC Neurology

Review Article Volume 17 Issue 4 - 2025

Kindling and Posttraumatic Stress Disorder, “Extinguishing the Fire”- An Insight into an Alternative Pharmaco Therapeutic Intervention

Patel Prithvi1, Hernandez Cecilia1 and Ullal Gautam2*

1American University of the Caribbean School of Medicine, Sint Maarten 2Professor of Neurology and Chair Basic Medical Sciences, American University School of Caribbean, Sint Maarten

*Corresponding Author: Ullal Gautam, Professor of Neurology and Chair Basic Medical Sciences, American University School of Caribbean, Sint Maarten.
Received: January 30, 2025; Published: March 07, 2025



Several studies have reported that PTSD is refractory to treatment, leaving patients with a poor prognosis. Medications used such as SSRIs and benzodiazepines are stated in previous studies as alleviating agents without the induction of remission. Here we report the neuronal model known as kindling to show a commonality between PTSD and epilepsy. This similarity between epilepsy and kindling opens the opportunity to treat PTSD with medications currently used in epileptic patients.

 Keywords: Posttraumatic Stress Disorder; Kindling; Antiepileptic Medications

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Ullal Gautam., et al. “Kindling and Posttraumatic Stress Disorder, “Extinguishing the Fire”- An Insight into an Alternative Pharmaco Therapeutic Intervention”. EC Neurology  17.4 (2025): 01-05.