EC Neurology

Holoprosencephaly is a rare brain anomaly that results from incomplete cleavage of the primitive forebrain prosencephalon during early embryogenesis. It includes several rare complex and heterogeneous disorders. The alobar form is associated with an unfavorable fetal prognosis. The aim of this observation is to review the different aspects of holoprosencephaly through a case of alobar holoprosencephaly diagnosed on a cerebral CT scan in the presence of congenital hydrocephalus without facial abnormalities of a 12-day-old female newborn.

Keywords: Alobar Holoprosencephaly; Hydrocephalus; CT Scan

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