Review Article Volume 17 Issue 7 - 2025

Deep Brain Stimulation in Parkinson’s Disease: Mechanisms, Targets, and Clinical Outcomes

Husam Abu Odeh*

Department of Medicine, Queen Alia Military Hospital, Amman, Jordan

*Corresponding Author: Husam Abu Odeh, Department of Medicine, Queen Alia Military Hospital, Amman, Jordan.
Received: May 14, 2025; Published: June 13, 2025



Parkinson’s disease (PD) is a progressive neurodegenerative disorder that primarily affects motor function due to the loss of function of the dopamine producing brain cells in substantia nigra. New neurosurgical interventions have emerged, including Deep Brain Stimulation, particularly when pharmacological treatments become less effective. This paper discusses the mechanism of DBS, brain structures involved, and the clinical results associated with its application in PD patients.

 Keywords: Parkinson’s Disease (PD); Deep Brain Stimulation; Sub Thalamic Nucleus (STN); Globus Pallidus Internus (GPi); Ventral Intermediate Nucleus (VIM)

 

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Husam Abu Odeh. “Deep Brain Stimulation in Parkinson’s Disease: Mechanisms, Targets, and Clinical Outcomes”. EC Neurology  17.7 (2025): 01-03.