EC Neurology

Lennox-Gastaut Syndrome (LGS) is a severe childhood-onset epileptic encephalopathy characterized by multiple seizure types, cognitive impairment, and distinct electroencephalographic (EEG) features. We report the case of a 6-year-old boy with medically intractable epilepsy, abnormal neurodevelopment, and MRI findings consistent with periventricular leukomalacia. Despite multiple antiepileptic drugs, seizures persisted. Prolonged EEG confirmed epileptogenic activity in bilateral posterior regions. The patient was deemed unsuitable for epilepsy surgery. Optimization of valproate dosage and initiation of levetiracetam were recommended.

 Keywords: Lennox-Gastaut Syndrome; Epilepsy; Antiepileptic Drugs; Case Report

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