EC Neurology

Case Report Volume 17 Issue 9 - 2025

A Rare Association between Congenital Strabismus and Cortical Malformations: MRI Evidence of Grey Matter Heterotopia

Jabour Soukayna*, Lahfidi Amal, Elaitari Khadija, Boujida Nadia, Khamlichi Amina, Fikri Meriem, Toursa Firdaous, Echcherif Kettani Najwa and Jiddane Mohamed

Department of Neuroradiology, University of Mohammed V of Rabat, Morocco

*Corresponding Author: Jabour Soukayna, Department of Neuroradiology, University of Mohammed V of Rabat, Morocco.
Received: July 21, 2025; Published: August 19, 2025



Congenital strabismus is most often attributed to abnormalities of the extraocular muscles or cranial nerves. However, emerging neuroimaging data suggest that cortical developmental anomalies may play an underrecognized role in it’s pathogenesis.

We report the case of a 35-year-old male presenting with longstanding, non-progressive strabismus since early childhood, with no history of trauma, perinatal complications, or neuromuscular disease. Brain MRI revealed nodular heterotopia of grey matter located along the lateral ventricular walls in the occipital region, with no other major structural anomalies. This malformation of cortical development was isointense to cortical grey matter across all MRI sequences, confirming the diagnosis of occipital periventricular grey matter heterotopia.

 Keywords: Strabismus; Grey Matter Heterotopia; MRI; Occipital Region

Jabour Soukayna., et al. “A Rare Association between Congenital Strabismus and Cortical Malformations: MRI Evidence of Grey Matter Heterotopia”. EC Neurology  17.9 (2025): 01-05.

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