EC Microbiology

Short Communication Volume 20 Issue 9 - 2024

Thalidomide Revisited: Advances in Medical Research on Chiral Pharmaceutical Intermediates

Maria Luigia Pallotta*

Department of Medicine and Health Sciences, University of Molise, Italy

*Corresponding Author: Maria Luigia Pallotta, Department of Medicine and Health Sciences, University of Molise, Italy.
Received: July 17, 2024; Published: August 30, 2024




The rate of metabolism as well as the metabolic profiles of the enantiomers and the racemate of 2-(2,6-dioxopiperidine-3-yl)-phthalimidine (EM12), a teratogenic thalidomide analogue, were investigated in vitro and in the marmoset monkey in vivo and published in 1989, by 3 researchers (Hans-Josefì Schmahl, Wolfgang Heger and Heinz Nau) from Institut für Toxikologie und Embryopharmakologie, Freie Universität, Berlin, German.

Maria Luigia Pallotta. “Thalidomide Revisited: Advances in Medical Research on Chiral Pharmaceutical Intermediates”. EC Microbiology  20.9 (2024): 01-04.

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