Research Article Volume 22 Issue 2 - 2026

Syzygium aromaticum and Zingiber officinale: A Promising Duo for Male Fertility, Cardiovascular and Renal Health

Didiane Méfokou Yemele1,2*, Leïla Djamilatou3, Sadiaa Halimatou1, Richard Dama1, Romuald Gbayara Ndjida1 and Sélestin sokeng Dongmo4

1Department of Biomedical Sciences, Faculty of Sciences, University of Ngaoundere, P.O. Box 455, Ngaoundere, Cameroon

2Ngaoundere Sunshine Diagnostics Research Laboratory, Ngaoundere, Cameroon

3Faculty of Medecine and Biomedical Sciences, University of Garoua, Cameroon

4Department of Biolocal Sciences, Faculty of Sciences, University of Ngaoundere, P.O. Box 455, Ngaoundere, Cameroon

*Corresponding Author: Didiane Méfokou Yemele, Department of Biomedical Sciences, Faculty of Sciences, University of Ngaoundere, P.O. Box 455, Ngaoundere, Cameroon and Ngaoundere Sunshine Diagnostics Research Laboratory, Ngaoundere, Cameroon.
Received: March 18, 2025; Published: January 22, 2026



Reproduction is a process that ensures the survival of an organism by passing on life and forming a new living being. Unfortunately, several couples face a variety of reproductive health issues, including infertility. Male infertility is a common issue that can be caused by a variety of factors, including hormonal changes. In the city of Ngaoundéré, traditional practitioners play a significant role in the care of individuals suffering from this disease. These practitioners use plants and traditional remedies to improve fertility. The overall goal of this study was to assess the effect of an aqueous extract of Syzygium aromaticum and Zingiber officinale on male reproductive function.

The various dosages of extract were prepared in the manner specified by the practitioner. The treatment of the animals consisted of administering different doses of extract (146, 292 and 584 mg/kg) on a daily basis, as well as controls. During the week-long treatment, the animals were divided into five groups of four animals each, and they received appropriate treatment every day between 7 a.m. and 10 a.m. using an endoscopic sonde. At the end of the 8-day treatment, these individuals were sacrificed, and their blood and organs were collected for various studies following established protocols.

The results of this study showed that administering the extract at a concentration of 292 mg/kg causes a significant increase in the levels of testosterone and FSH, implying that these plants stimulate reproductive function, justifying their traditional use in the treatment of male infertility. The use of toxicity markers has also demonstrated that administering various amounts of these extracts has no adverse effects on the consumer.

 Keywords: Male Infertility; Traditional Practitioners; Traditional Plants; Toxicity

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Didiane Méfokou Yemele., et al.Syzygium aromaticum and Zingiber officinale: A Promising Duo for Male Fertility, Cardiovascular and Renal Health”. EC Microbiology  22.2 (2026): 01-09.