EC Microbiology

Research Article Volume 19 Issue 3 - 2023

Peptide Properties of Saccharomyces arboricola H-6 Suggest Randomness in Chromosomal Organization

Daeun Roh1,2, Shah Yunn Naing1,2 and Maurice HT Ling1,2,3*

1School of Life Sciences, Management Development Institute of Singapore, Singapore

2School of Applied Sciences, Northumbria University, United Kingdom

3HOHY PTE LTD, Singapore

*Corresponding Author: Maurice HT Ling, School of Life Sciences, Management Development Institute of Singapore and School of Applied Sciences, Northumbria University, United Kingdom and HOHY PTE LTD, Singapore.
Received: February 02, 2023; Published: February 28, 2023



Eukaryotic genomes are organized into multiple chromosomes and studies have suggested that chromosomal organization is subjected to evolutionary pressure as demonstrated by non-randomness of properties across chromosomes. However, a recent study provided evidence to suggest that chromosomal organization may be more random in unicellular than multicellular eukaryotes. Here, we examine the distribution of five peptide features (length, aromaticity, instability, hydropathy, and isoelectric point) across the 16 nuclear chromosomes of Saccharomyces arboricola H-6, a recently identified and sequenced unicellular eukaryote. Our results show that only hydropathy is not random across the chromosomes (F = 1.914, p-value = 0.018); thereby, supporting the hypothesis that chromosomal organization may be random in unicellular eukaryotes.

Keywords: Peptide Properties; Saccharomyces arboricola H-6; Chromosomal Organization

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Maurice HT Ling., et al. “Peptide Properties of Saccharomyces arboricola H-6 Suggest Randomness in Chromosomal Organization”. EC Microbiology  19.3 (2023): 01-08.

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