EC Microbiology
Review Article Volume 22 Issue 11 - 2026

Pathogenesis of Acute Pancreatitis

Andrija Badanjak1 and Gordana Blagojević Zagorac2,3*

1Health Centre Popovača, Croatia
2Medical Faculty, University of Rijeka, Rijeka, Croatia
3University North, Varaždin, Croatia

*Corresponding Author: Gordana Blagojević Zagorac, Professor, Department of Physiology, Immunology and Pathophisiology, Medical Faculty, University of Rijeka, Croatia.
Received: October 13, 2026; Published: October 30, 2026



Acute pancreatitis is an acute inflammation of the exocrine pancreas and is considered a common and severe disease. The most common etiological factors are excessive alcohol consumption and gallstones. The disease has a sudden onset and may rapidly prog- ress to a severe and potentially life-threatening condition. Treatment of acute pancreatitis is primarily conservative and largely based on supportive care and to date, no specific targeted pharmacological therapy for acute pancreatitis has been developed. A better understanding of the pathogenesis of acute pancreatitis may facilitate the identification of key molecular and cellular mechanisms involved in pancreatic inflammation and contribute to the discovery of novel, more specific therapeutic approaches targeting factors that play an important role. This review summarizes current knowledge of the pathogenesis of acute pancreatitis.

Keywords:

Acute Pancreatitis (AP); Pathogenesis; Pancreatic Inflammation; Systemic Inflammatory Response Syndrome (SIRS).

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Andrija Badanjak and Gordana Blagojević Zagorac. “Pathogenesis of Acute Pancreatitis”. EC Microbiology 22.11 (2026): 01-07.

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