EC Microbiology

Research Article Volume 18 Issue 10 - 2022

Overview of Management and Prognosis of Obstructive Sleep Apnea

Jehad Mohammed fadel M Bukhari1*, Khaled Seralkhatim Mohammed2, Mohamedelhassan Hamza Ashabi2, Nebras Mohammed Fayoumi3, Hamad Abdulrahman Algaeed4, Mujahid Salih Aldhaif4, Shahad Abdullah Badawood5, Musaab Abdullah Badawood6, Mayssan Hussein Ali Almalki5, Ahmed Saeed Alzahrani6, Sultan Abdullah Al Essa7, Nada Ayed Allugmani8, Mohammed Muthyib Almuawi9 and Saud Khalid Alsamadani10

1King abdulaziz hospital, Jeddah, Saudi Arabia
2Saudi Red crescent authority, Riyadh, Saudi Arabia
3kol alosrah pharmacy - Taif- Saudi Arabia
4King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia
5king Abdullah Medical Complex, Jeddah, Saudi Arabia
6Bahra Primary health care, Makkah, Saudi Arabia
7Ministry of health, Makkah, Saudi Arabia
8durrat al madina primary health care, Medina, Saudi Arabia
9King Abduallah Hospital, Bisha, Saudi Arabia
10King Fahad Medical City, Riyadh, Saudi Arabia

*Corresponding Author: Jehad Mohammed Fadel M Bukhari, King Abdulaziz Hospital, Jeddah, Saudi Arabia.
Received: September 01, 2022; Published: September 14, 2022



Introduction: In Obstructive sleep apnea, the upper airway is compromised during sleep leading to episodes of apnea and hypopnea. The condition is more pronounced while sleeping supine and is more common among middle-aged obese males. A sedentary lifestyle, smoking and consumption of alcohol can predispose to OSA. Moreover, chronic sleep apnea also predisposes to several metabolic and cardiovascular disorders. In this review, we shall discuss the various modalities of managing OSA and their prognosis.

Aim of Work: The aim of this study is to discuss the management and prognosis of OSA.

Materials and Methods: Comprehensive research of obstructive sleep apnea. PUBMED search engine were the mainly used database for search process, articles collected from the year 1991 to 2020 relating to obstructive sleep apnea. The term used in search were: obstructive sleep apnea - sleep apnea - hypopnea.

Conclusion: Sleep apnea is prevalent due to anatomical obstruction of the airway of many affected individuals during sleep. It can predispose to many cardiovascular and metabolic disorders. Several methodologies of management, ranging from simple aerobic exercises to complex surgical procedures, have been incorporated into practice. A detailed history of OSA, a thorough investigation and a proper treatment plan can successfully manage most cases.

 

Keywords: Obstructive Sleep Apnea; Sleep Apnea; Hypopnea

  1. Medeiros CAM., et al. “Neck circumference, a bedside clinical feature related to mortality of acute ischemic stroke”. Revista da Associação Médica Brasileira 57 (2011): 559-564.
  2. Jordan AS., et al. “Adult obstructive sleep apnoea”. The Lancet9918 (2014): 736-747.
  3. Peppard PE., et al. “Increased prevalence of sleep-disordered breathing in adults”. American Journal of Epidemiology9 (2013): 1006-1014.
  4. Gottlieb DJ and Punjabi NM. “Diagnosis and management of obstructive sleep apnea: a review”. The Journal of the American Medical Association14 (2020): 1389-1400.
  5. Dempsey JA., et al. “Pathophysiology of sleep apnea”. Physiological Reviews 1 (2010): 47-112.
  6. Somers VK., et al. “Sleep apnea and cardiovascular disease: An American heart association/American college of cardiology foundation scientific statement from the American heart association council for high blood pressure research professional education committee, council on clinical cardiology, stroke council, and council on cardiovascular nursing in collaboration with the national heart, lung, and blood institute national center on sleep disorders research (national institutes of health)”. Journal of the American College of Cardiology8 (2008): 686-717.
  7. Guilleminault C., et al. “A clinical investigation of obstructive sleep apnea syndrome (OSAS) and upper airway resistance syndrome (UARS) patients”. Sleep Medicine1 (2000): 51-56.
  8. Netzer NC., et al. “Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome”. Annals of Internal Medicine7 (1999): 485-491.
  9. Kapur VK., et al. “Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline”. Journal of Clinical Sleep Medicine3 (2017): 479-504.
  10. Hudgel DW., et al. “The role of weight management in the treatment of adult obstructive sleep apnea. An official American Thoracic Society clinical practice guideline”. American Journal of Respiratory and Critical Care Medicine6 (2018): e70-e87.
  11. Schwartz AR., et al. “Effect of weight loss on upper airway collapsibility in obstructive sleep apnea1-3”. The American Review of Respiratory Disease3-1 (1991): 494-498.
  12. Vincent HK., et al. “Adaptation of upper airway muscles to chronic endurance exercise”. American Journal of Respiratory and Critical Care Medicine3 (2002): 287-293.
  13. Shiota S., et al. “Alterations in upper airway cross-sectional area in response to lower body positive pressure in healthy subjects”. Thorax10 (2007): 868-872.
  14. Choi JH., et al. “Efficacy study of a vest-type device for positional therapy in position dependent snorers”. Sleep and Biological Rhythms3 (2009): 181-187.
  15. Lance CG. “Positive airway pressure: Making an impact on sleep apnea”. Cleveland Clinic Journal of Medicine9-1 (2019): 26-33.
  16. Jayesh SR and Bhat WM. “Mandibular advancement device for obstructive sleep apnea: An overview”. Journal of Pharmacy and Bioallied Sciences1 (2015): S223.
  17. Singh GD., et al. “Biomimetic oral appliance therapy in adults with severe obstructive sleep apnea”. Journal of Sleep Disorders and Therapy227 (2016): 2167-0277.
  18. Wadhera V and Fogarty G. “Uvulopalatopharyngoplasty: a specific surgical technique aimed at minimising patient morbidity, with outcomes over 5 years in a regional centre”. Australian Journal of Otolaryngology (2020): 3.
  19. Aneeza WH., et al. “Effects of uvulopalatopharyngoplasty: a seven year review”. The Medical Journal of Malaysia2 (2011): 129-132.
  20. Kwon M., et al. “The effect of uvula-preserving palatopharyngoplasty in obstructive sleep apnea on globus sense and positional dependency”. Clinical and Experimental Otorhinolaryngology3 (2010): 141-146.
  21. Varghese R., et al. “Maxillomandibular advancement in the management of obstructive sleep apnea”. International Journal of Otolaryngology (2012).
  22. Zaghi S., et al. “Maxillomandibular advancement for treatment of obstructive sleep apnea: a meta-analysis”. JAMA Otolaryngology–Head and Neck Surgery1 (2016): 58-66.
  23. Chen YF., et al. “Hypoglossal nerve stimulation for treatment of obstructive sleep apnea (OSA): a primer for oral and maxillofacial surgeons”. Maxillofacial Plastic and Reconstructive Surgery1 (2017): 1-5.
  24. Baptista P., et al. “Upper Airway Stimulation in the Management of Obstructive Sleep Apnea Syndrome: Neurostimulation of Hypoglossal Nerve”. International Journal of Head and Neck Surgery4 (2019): 77-85.

Jehad Mohammed Fadel M Bukhari., et al. Correlation Analysis on Transcriptomes from Published Human Skin Studies Show Variations between Control Samples. EC Clinical and Medical Case Reports  5.8 (2022): 143-146.