EC Microbiology

This research aims to evaluate the capacity of specific microorganisms, namely lactobacilli and other lactic acid bacteria (LAB), to eradicate antibiotic-resistant pathogens and establish novel therapeutic strategies. The increasing failure of conventional antibiotics against resistant strains underscores the critical need for effective alternatives. Lactobacilli have emerged as a promising candidate, demonstrating the ability to reduce pathogen virulence through multiple mechanisms, including the production of bioactive substances, competition for resources, and coaggregation. Beyond their antimicrobial activity, prolonged administration of these probiotics induces beneficial modifications in the gastrointestinal microbiome. This review summarizes the supporting evidence for lactobacilli's efficacy in treating various pathological conditions, including digestive disorders like diarrhea, metabolic imbalances, and even broader applications in kidney and pancreatic health, cancer prevention, and immune modulation. With their proven safety profile and multifaceted mode of action, Lactobacilli represent a viable, safe, and cost-effective alternative for combating resistant infections and promoting overall health.

 Keywords: Probiotic Bacteria; Treatment of Pathogenic Bacteria; Aantibiotic-Resistant Bacteria; Saccharomyces

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