EC Microbiology

Review Article Volume 16 Issue 12 - 2020

Effect of COVID-19 Pandemic Lockdowns on Cervical and Breast Screening and Follow Ups in the Primary Health Care Setting: Literature Review

Muhammad Mubashir Niaz1*, Ahmed Marzouq Alamri2, Orjuwan Abdulbari Mazi3, Esra Abdulrahman Majrashi4, Lulwa Faisal Alaradi5, Othman Mohammed Bahattab2, Amnah Makki Al Abdulwahab6, Abdullah Khalid Alomar7, Abdulmalik Ahmed Bakhsh8, Bandar Waleed AlmeerAbdullah9 and Mansour Adel Shourbaji9

1Obstetrics and Gynecology Specialist, Department of Obstetrics and Gynecology, Khulais General Hospital, Khulais, Saudi Arabia
2General Physician, Ministry of Health, Makkah, Saudi Arabia
3General Physician, Ministry of Health, Jeddah, Saudi Arabia
4College of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia
5General Physician, Al Kindi Hospital, Manama, Bahrain 6GGeneral Physician, Ministry of Health, Albatha Hospital, Al Batha, Saudi Arabia
7General Practice, Ministry of Health, Al Ahsa, Saudi Arabia
8College of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
9College of Medicine, Medical University of Lodz, Lodz, Poland

*Corresponding Author:Muhammad Mubashir Niaz, Obstetrics and Gynecology Specialist, Department of Obstetrics and Gynecology, Khulais General Hospital, Khulais, Saudi Arabia.
Received: November 11, 2020; Published: November 28, 2020


The newly emerging coronavirus has affected many fields in the healthcare systems. Many resources have been declared lacking due to the high consumption during the pandemic. Among the fields that were hugely affected, cancer care is one of them that requires more attention to save what can be saved. In this review, we aimed to shed more insight into how the lockdown affected the screening and follow-up procedures of both the breast and cervix. Since the start of the pandemic, reports showed that lacking continuous screening and follow-up was remarkable which may have affected the prognosis for many potential breast and cervical cancers. These showed that delays in diagnosis and screening may have increased the incidence of mortality from breast and cervical cancers. However, many recommendations have been proposed by many relevant organizations to reduce this burden and also control the spread of the pandemic. Personal protective measures and reducing the number of individuals visiting a hospital per day are maybe the most highlighted measures. Follow-ups have been also organized to be through telemedicine for non-severe cases, and in-person and/or at a primary healthcare hospital for severe cases requiring frequent follow-up.

Keywords: Lockdown; Pandemic; COVID-19; Breast; Cervix

  1. Bibliography 1. Wu F., et al. “A new coronavirus associated with human respiratory disease in China”. Nature 579.7798 (2020): 265-269.
  2. Lu R., et al. “Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding”. Lancet 395.10224 (2020): 565-574.
  3. Gupta A., et al. “Extrapulmonary manifestations of COVID-19”. Nature Medicine 26.7 (2020): 1017-1032.
  4. Barda N., et al. “Developing a COVID-19 mortality risk prediction model when individual-level data are not available”. Nature Communications 11.1 (2020): 4439.
  5. Gibson DM and Greene J. “Risk for Severe COVID-19 Illness Among Health Care Workers Who Work Directly with Patients”. Journal of General Internal Medicine 35.9 (2020): 2804-2806.
  6. Richardson S., et al. “Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area”. The Journal of the American Medical Association 323.20 (2020): 2052-2059.
  7. Liang W., et al. “Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China”. The Lancet Oncology 21.3 (2020): 335-337.
  8. Yu J., et al. “SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China”. JAMA Oncology 6.7 (2020): 1108-1110.
  9. Zhang L., et al. “Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China”. Annals of Oncology 31.7 (2020): 894-901.
  10. Razi S., et al. “Changing Trends of Types of Skin Cancer in Iran”. Asian Pacific Journal of Cancer Prevention: APJCP 16 (2015): 4955- 4958.
  11. Zahedi A., et al. “Incidence, Trends and Epidemiology of Cancers in North West of Iran”. Asian Pacific Journal of Cancer Prevention 16 (2015): 7189-7193.
  12. Ferlay J., et al. “Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012”. International Journal of Cancer 136.5 (2015): E359-E386.
  13. Clegg LX., et al. “Impact of socioeconomic status on cancer incidence and stage at diagnosis: selected findings from the surveillance, epidemiology, and end results: National Longitudinal Mortality Study”. Cancer Causes Control 20.4 (2009): 417-435.
  14. Ghoncheh M., et al. “Incidence and Mortality and Epidemiology of Breast Cancer in the World”. Asian Pacific Journal of Cancer Prevention 17 (2016): 43-46.
  15. Arbyn M., et al. “Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis”. The Lancet Global Health (2019): 8.
  16. Hollander JE and Carr BG. “Virtually perfect? Telemedicine for COVID-19”. New England Journal of Medicine 382.18 (2020): 1679- 1681.
  17. Ueda M., et al. “Managing cancer care during the COVID-19 pandemic: agility and collaboration toward a common goal”. Journal of the National Comprehensive Cancer Network 1 (2020): 1-4.
  18. Wong GL-H., et al. “Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement”. The Lancet Gastroenterology and Hepatology (2020).
  19. Liang W., et al. “Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China”. The Lancet Oncology 21.3 (2020): 335-337.
  20. Curigliano G., et al. “Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic”. Breast 52 (2020): 8-16.
  21. De Azambuja E., et al. “ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer”. ESMO Open 5.3 (2020): e000793.
  22. Citgez B., et al. “Management of Breast Cancer during the COVID-19 Pandemic”. Sisli Etfal Hastanesi Tip Bülteni 54.2 (2020): 132-135.
  23. London JW., et al. “Effects of the COVID-19 Pandemic on Cancer-Related Patient Encounters”. JCO Clinical Cancer Informatics 4 (2020): 657-665.
  24. Kowalczyk L. “Major Boston hospital finds dramatic drop in stroke, heart attack, and cancer patients during coronavirus pandemic”. Boston Globe 5.18 (2020): 2020.
  25. London JW., et al. “Effects of the COVID-19 pandemic on cancer-related patient encounters”. JCO Clinical Cancer Informatics 4 (2020): 657-665.
  26. Printz C. “Cancer screenings decline significantly during pandemic”. Cancer 126.17 (2020): 3894.
  27. Tsai H-Y., et al. “Effects of the COVID-19 pandemic on breast cancer screening in Taiwan”. The Breast 54 (2020): -55.
  28. Peng S-M., et al. “Impact of the COVID-19 pandemic on a population-based breast cancer screening program”. Cancer.n/a(n/a) 126.24 (2020): 5202-5205.
  29. Wilson R. “COVID-19 Sidelines Breast Cancer Screening”. LWW (2020).
  30. Bambhroliya A., et al. “Barriers to the use of breast cancer risk reduction therapies”. Journal of the National Comprehensive Cancer Network 13.7 (2015): 927-935.
  31. Çağlayan Ç., et al. “Assessing Multi-Modality Breast Cancer Screening Strategies for BRCA 1/2 Gene Mutation Carriers and Other HighRisk Populations (2018).
  32. Arbyn M., et al. “Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis”. The Lancet Global Health 8.2 (2020): e191-e203.
  33. Del Pilar Estevez-Diz M., et al. “Management of cervical cancer patients during the COVID-19 pandemic: a challenge for developing countries”. Ecancer Medical Science 14 (2020): 1060.
  34. Kirigia C. “Cervical Cancer Screening during the COVID-19 Crisis: Africa View Point”. SSRN Electronic Journal (2020).
  35. Lambertini M., et al. “Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists’ perspective”. British Medical Journal (2020).
  36. Colombo I., et al. “ESMO management and treatment adapted recommendations in the COVID-19 era: gynaecological malignancies”. ESMO Open 5.3 (2020): e000827.
  37. Greenwood E and Swanton C. “Consequences of COVID-19 for cancer care - a CRUK perspective”. Nature Reviews Clinical Oncology (2020).
  38. Maringe C., et al. “The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study”. The Lancet Oncology (2020): 21.
  39. Hanna TP., et al. “Mortality due to cancer treatment delay: systematic review and meta-analysis”. British Medical Journal 371 (2020): m4087.
  40. Sharpless NE. “COVID-19 and cancer”. American Association for the Advancement of Science (2020).
  41. Maringe C., et al. “The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study”. The Lancet Oncology 21.8 (2020): 1023-1034.

Muhammad Mubashir Niaz., et al. “Effect of COVID-19 Pandemic Lockdowns on Cervical and Breast Screening and Follow Ups in the Primary Health Care Setting: Literature Review”. EC Microbiology  16.12 (2020): 68-74.