EC Pharmacology and Toxicology

The main aim of the present study was to analyze and evaluate the bioactive compounds from hexanic extract of moss Bryum argenteum Hedw.’s non-polar (hexane) extract using UV-Visible spectroscopy, Fourier Transform Infrared spectroscopy (FT-IR) and Gas Chromatography Mass Spectroscopy (GC-MS) techniques. Spectral data of UV-Visible analysis revealed the presence of flavonoids, phenolics compounds and terpenoids, and FTIR spectra’s absorption peaks displayed distinct vibrational stretching including ‘C-H, C-O, C-N, C=C and O-H bending’ and supporting the presence of lipophilic substances, including alkyne, alkane, aromatic compounds, alcohol, alkene, phenols and amine. Hexane extract’s GC-MS investigation resulted a complex profile of thirty-three semi-volatile and volatile bio-active compounds. With an 84.96% of peak-area, the non-polar molecule, 2,4-dimethyl-pentane was the principal compound of moss’s hexane extract. These uncovered secondary-metabolites displayed differ pharmaceutical values like anti-bacterial, anti-cancerous, allelopathic, hypocholesterolemic, anti-candidal anti-oxidant, nematicide, and anti-inflammatory. This research’s combined analytical analysis, highlights the chemical diversity of Bryum argenteum’s hexane extract and suggests that its non-polar metabolites may have pharmacological significance in drug-discovery. Further investigations must be concentrated on detailed bioassay and structural clarifications of individual moss-derived natural compounds.

 Keywords: Bryum argenteum Hedw.; Moss; Hexane Extract; UV-Visible Spectroscopy; FTIR; GC-MS

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