EC Pharmacology and Toxicology

Review Article Volume 11 Issue 1 - 2023

Biochemical and Histological Features of Aspirin Toxicity

Ahed J Alkhatib1,2*, Khalid Mohammad Albakiri3, Bader Salem Alanazi3 and Hamed Zuhir Alqarni4

1Department of Legal Medicine, Toxicology and Forensic Medicine, Jordan University of Science and Technology, Irbid, Jordan
2International Mariinskaya Academy, Department of Medicine and Critical Care, Department of Philosophy, Academician Secretary of the Department of Sociology, Irbid, Jordan
3Poison Control Center in Riyadh, KSA
4Poison Control Center and Forensic Medicinal Chemistry, KSA

*Corresponding Author: Ahed J Alkhatib, Department of Legal Medicine, Toxicology and Forensic Medicine, Jordan University of Science and Technology and International Mariinskaya Academy, Department of Medicine and Critical Care, Department of Philosophy, Academician Secretary of the Department of Sociology, Irbid, Jordan.
Received: November 22, 2022; Published: December 29, 2022



The anti-inflammatory and pain-relieving effects of aspirin have been known to science and widely used for quite some time. The list of applications for this compound continues to grow, and it now includes anti-inflammatory and anti-platelet activities. It is not necessary to place an undue amount of emphasis on the part it plays in cardiovascular diseases because of this. This study aimed to conduct a literature review on the topic of the toxicity that can be caused by the use of aspirin, with the purpose of answering the following question: The toxicity that it primarily causes over a prolonged period of time has an effect on the upper gastrointestinal system. It is also capable of causing acute toxicity if consumed in sufficient quantities to reach that threshold. When everything is taken into account, the significance of aspirin and the widespread use of the drug should not be used as an excuse to disregard the drug's potential for toxicity. Instead, treating physicians should conduct clinical evaluations of their patients in addition to any necessary blood, liver, and kidney function tests.

Keywords: Aspirin; Toxicity; Liver Function Test; Kidney Function Test; Chronic Toxicity

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Ahed J Alkhatib.,et al. Biochemical and Histological Features of Aspirin Toxicity. EC Pharmacology and Toxicology 11.1 (2023): 36-41.