EC Paediatrics

Review Article Volume 13 Issue 5 - 2025

A Comprehensive Review on the Assessment of the Treatment of Cerebral Palsy in Patients with Cerebral Palsy

Kabra Vinay S*, Gaikwad Rohan D, Padole Rushikesh G, Kapse (Yalam) Vidya and Dharashive VM

Pharmacy Practice Department, Shivlingeshwar College of Pharmacy, Almala, Ausa, Latur, Maharashtra, India

*Corresponding Author: Kabra Vinay S, Pharmacy Practice Department, Shivlingeshwar College of Pharmacy, Almala, Ausa, Latur, Maharashtra, India.
Received: April 09, 2025; Published: April 29, 2025



Cerebral palsy (CP) is a complex neurological disorder affecting movement, muscle tone, and posture due to brain abnormalities that occur before, during, or shortly after birth. Treatment strategies, including pharmacological, therapeutic, and surgical interventions, aim to enhance motor function and overall quality of life. Assessing the efficacy of these interventions is essential to optimizing patient outcomes. This review provides a comprehensive analysis of treatment modalities, discusses assessment methodologies, and explores emerging advancements such as gene therapy, artificial intelligence, and robotics in rehabilitation.

The current body of research underscores the importance of a multidisciplinary approach tailored to the unique needs of each CP patient. This paper delves into various pharmacological agents used for spasticity and pain management, the significance of physical and occupational therapies, and the effectiveness of surgical interventions. Additionally, complementary and alternative therapies such as acupuncture and hydrotherapy are examined for their potential benefits. The review concludes with insights into future research directions, emphasizing the role of precision medicine and technological innovations in advancing CP treatment paradigms [4,11,12,14,15].

 Keywords: Cerebral Palsy; Treatment Evaluation; Rehabilitation; Spasticity Management; Neurological Disorders

  1. Jindal P., et al. “Treatment and rehabilitation of children with cerebral palsy in India: a scoping review”. Developmental Medicine and Child Neurology9 (2019): 1050-1060.
  2. Gowda VK. “Recent advances in cerebral palsy”. Karnataka Paediatric Journal 1 (2020): 4-18.
  3. Shukla D. “Socio-demographic and clinical profile of pediatric patients with cerebral palsy in Gujarat, India”. Bulletin of Faculty of Physical Therapy 27 (2022): 19.
  4. Kumar R., et al. “Recent advancements in interventions for cerebral palsy - A review”. Journal of Clinical Orthopaedics and Trauma 24 (2023): 101746.
  5. India State-Level Disease Burden Initiative Neurological Disorders Collaborators. “The burden of neurological disorders across the states of India: the Global Burden of Disease Study 1990-2019”. The Lancet Global Health 8 (2021): e1129-e1144.
  6. Sankar C and Mundkur N. “Cerebral palsy-definition, classification, etiology and early diagnosis”. Indian Journal of Pediatrics 10 (2005): 865-868.
  7. Arora RS., et al. “Prevalence of cerebral palsy in Indian children: a systematic review and meta-analysis”. Indian Journal of Pediatrics 11 (2020): 976-981.
  8. Khanna S., et al. “Neurodevelopmental treatment in children with cerebral palsy: a review of the literature”. Cureus12 (2023): e50389.
  9. Pani SK., et al. “Case report on cerebral palsy with Ayurvedic treatment protocol”. Journal of Pharmaceutical Research International 43A (2021): 47-50.
  10. Ghosh S and Dey SK. “Quality of life of children with cerebral palsy: evidence from Assam, India”. Disability and Health Journal 2 (2024): 101182.
  11. Indian Academy of Pediatrics. “Cerebral palsy”. In: Kamath SS, Ratageri VH, eds. IAP Standard Treatment Guidelines (2022): 188-193.
  12. Patel DR., et al. “Cerebral palsy in children: a clinical overview”. Translational Pediatrics 1 (2020): S125-S135.
  13. Brunstrom-Hernandez J. “The gross motor function classification system (GMFCS) explained”. Developmental Medicine and Child Neurology 1 (2017): 79-80.
  14. Graham D., et al. “The effect of botulinum toxin A on walking in children with cerebral palsy: a randomized controlled trial”. Developmental Medicine and Child Neurology 10 (2008): 719-725.
  15. Novak I., et al. “State of the evidence traffic lights 2019: systematic review of interventions for preventing and treating children with cerebral palsy”. Current Neurology and Neuroscience Reports 2 (2020): 3.
  16. Park TS and Owen JH. “Surgical management of spasticity in cerebral palsy”. Seminars in Pediatric Neurology 2 (2002): 81-87.
  17. Tedroff K., et al. “Selective dorsal rhizotomy in children with cerebral palsy: a 10-year follow-up study”. Developmental Medicine and Child Neurology 5 (2015): 484-490.
  18. Delgado MR and Albright AL. “Movement disorders in children: definitions, classifications, and grading schemes”. Journal of Child Neurology 1 (2003): S1-S8.
  19. Christensen E and Melchior JC. “Risk factors for cerebral palsy in children”. Early Human Development 1-2 (1993): 57-72.
  20. Reddihough DS and Collins KJ. “The epidemiology and causes of cerebral palsy”. Australian Journal of Physiotherapy 1 (2003): 7-12.
  21. Anttila H., et al. “Effectiveness of physical therapy interventions for children with cerebral palsy: a systematic review”. Clinical Rehabilitation 9 (2008): 878-887.
  22. Fehlings D., et al. “A systematic review of the effectiveness of exercise programs for children with cerebral palsy: the state of the evidence”. Developmental Medicine and Child Neurology6 (2012): 499-505.
  23. Beckung E., et al. “Surveillance of cerebral palsy in Europe: a collaboration of cerebral palsy surveys and registers”. Developmental Medicine and Child Neurology8 (2007): 521-526.
  24. Himmelmann K., et al. “The changing panorama of cerebral palsy in Sweden. IX. Prevalence and origin in the birth-year period 1995-1998”. Acta Paediatrica3 (2005): 287-294.
  25. Bolajoko O Olusanya., et al. “Cerebral palsy and developmental intellectual disability in children younger than 5 years: Findings from the GBD-WHO Rehabilitation Database 2019”. Frontiers in Public Health 10 (2022).

Kabra Vinay S., et al. "A Comprehensive Review on the Assessment of the Treatment of Cerebral Palsy in Patients with Cerebral Palsy". EC Paediatrics 13.5 (2025): 01-08.