EC Ophthalmology

Case Study Volume 15 Issue 7 - 2024

Surgical Management of Posterior and Retracted Retinal Breaks with Amniotic Membrane Plugs: A Case Series

MD Najib Arsalan1*, PHD Muraine Marc1 and MD Lorenzi Umberto1

Department of Ophthalmology, Hospital Center of Rouen, University of Rouen, 76000, France

*Corresponding Author: Arsalan Najib, Department of Ophthalmology, Hospital Center of Rouen, University of Rouen, 76000, France.
Received: June 04, 2024; Published: July 02, 2024



Purpose: To evaluate mid-term safety and efficiency of a new surgical technique using amniotic membrane plugs for the treatment of posterior pole and/or retracted retinal breaks in tractional and delayed rhegmatogenous retinal detachment.

Methods: Patients with rhegmatogenous associated to at least grade C proliferative vitreoretinopathy or tractional retinal detachment with retinal breaks sealed by amniotic membrane plugs were included. Minimal follow-up of 12 months with visual acuity evaluation, optical coherence tomography, retinophotography, intraocular pressure and re-detachment rate evaluation at 1, 3, 6 and 12 months.

Results: 9 eyes of 9 patients were included. The mean 12-month post-operative best corrected visual acuity was 1.12 logMar. Fundus photography and optical coherence tomography shows that the plugs stayed in place at 1,3,6 and 12 months without dislocation. Glial tissue regeneration was noticed without original retinal layers restoration. Only one retinal re-detachment occurred after silicone oil removal. Neither elevation of intraocular pressure nor signs of inflammation were registered.

Conclusion: Amniotic membrane plugs represent safe and efficient surgical technique to manage posterior pole and/or retracted retinal breaks without the limitations of laser retinopexy.

 Keywords: Amniotic Membrane; Rhegmatogenous Retinal Detachment; Tractional Retinal Detachment; Vitreoretinal Proliferation; Vitreoretinal Surgery

  1. Haimann MH., et al. “Epidemiology of retinal detachment”. Archives of Ophthalmology 2 (1982): 289-292.
  2. Pastor JC. “Proliferative vitreoretinopathy: An overview”. Survey of Ophthalmology1 (1998): 3-18.
  3. Caporossi T., et al. “Human amniotic membrane to close recurrent, high myopic macular holes in pathologic myopia with axial length of ≥ 30 mm”. Retina10 (2020): 1946-1954.
  4. Newman DK. “Surgical management of the late complications of proliferative diabetic retinopathy”. Eye (London)3 (2010): 441-449.
  5. Subash M., et al. “The effect of multispot laser panretinal photocoagulation on retinal sensitivity and driving eligibility in patients with diabetic retinopathy”. JAMA Ophthalmology6 (2016): 666-672.
  6. Rizzo S., et al. “Autologous internal limiting membrane fragment transplantation for rhegmatogenous retinal detachment due to paravascular or juxtapapillary retinal breaks over patchy chorioretinal atrophy in pathologic myopia”. Retina1 (2018): 198-202.
  7. Chen Y-C., et al. “Lens capsular flap in the management of posterior retinal hole associated retinal detachment in high myopic eyes with previous internal limiting membrane peeling: 3 case reports”. Medicine (Baltimore) 29 (2019): e16422.
  8. Tosi GM., et al. “Disease pathways in proliferative vitreoretinopathy: an ongoing challenge”. Journal of Cellular Physiology 11 (2014): 1577-1583.
  9. Rizzo S., et al. “A human amniotic membrane plug to promote retinal breaks repair and recurrent macular hole closure”. Retina1 (2019): S95-S103.
  10. Navas A., et al. “Anti-inflammatory and anti-fibrotic effects of human amniotic membrane mesenchymal stem cells and their potential in corneal repair”. Stem Cells Translational Medicine 12 (2018): 906-917.

Arsalan Najib. "Surgical Management of Posterior and Retracted Retinal Breaks with Amniotic Membrane Plugs: A Case Series." EC Ophthalmology 15.7 (2024): 01-07.