EC Ophthalmology

Research Article Volume 14 Issue 12 - 2023

Increased Choroidal Blood Flow in Eyes with Macular Edema is Associated with Branch Retinal Vein Occlusion on Laser Speckle Flowgraphy

Ryuya Hashimoto*, Keisuke Yata, Sonoko Isa and Takatoshi Maeno

Department of Ophthalmology, Toho University Sakura Medical Center, Shimoshizu, Sakura, Japan

*Corresponding Author: Ryuya Hashimoto, Department of Ophthalmology, Toho University Sakura Medical Center, Shimoshizu, Sakura, Japan.
Received: November 19, 2023; Published: December 04, 2023




Purpose: To examine the choroidal blood flow (CBF) and vascular resistance (CVR) in eyes with treatment-naive non-ischemic branch retinal vein occlusion (BRVO).

Methods: We included 52 patients with BRVO (29 patients with major BRVO and 23 patients with macular BRVO) attending a university-related medical center. The CBF and CVR in the subfovea were measured via laser speckle flowgraphy (LSFG) and were compared between affected and fellow eyes of patients with major and macular BRVO.

Results: The mean CBF in the subfovea was significantly higher in affected (9.35 ± 4.65) than in fellow eyes (7.91 ± 3.07 P = 0.031) in the major BRVO group, whereas mean CBF was similar between affected (9.07 ± 2.92) and fellow eyes (8.56 ± 3.11, P = 0.649) in the macular BRVO group. The CVR in the subfovea was significantly lower in affected (7.28 ± 2.93) than in fellow eyes (8.32 ± 3.70, P = 0.020) in the major BRVO group. In contrast, there was no significant difference in the mean CVR between affected (6.97 ± 2.72) and fellow eyes (7.58 ± 2.89, P = 0.520) in the macular BRVO group. The CBF in the subfovea of the affected eye was significantly associated with the central retinal thickness (R = -0.307, P = 0.027).

Conclusion: Our data showed that the CBF in the subfovea is increased in eyes with major BRVO due to reduced CVR. An increase in CBF might compensate for the ischemic retina in patients with major BRVO.

 Keywords: Branch Retinal Vein Occlusion; Choroidal Blood Flow; Choroidal Thickness; Vascular Resistance; Laser Speckle Flowgraphy

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Ryuya Hashimoto., et al. "Increased Choroidal Blood Flow in Eyes with Macular Edema is Associated with Branch Retinal Vein Occlusion on Laser Speckle Flowgraphy." EC Ophthalmology 14.12 (2023): 01-13.

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