EC Ophthalmology

Research Article Volume 15 Issue 9 - 2024

Conventional Trabeculectomy vs. Sutureless Trabeculectomy in Patients with Uncontrolled Glaucoma: Structural and Functional Outcomes

Meisam Sargazi1*, Ahmad Davoodian1, Mohammad Arish1, Seyed Omid Mohammadi2 , Darya Najafi3 and SEYEDEH SANA SADATIPOUR4

1Ophthalmology, Zahedan University of Medical Sciences, Zahedan, Iran
2Anne Burnett Marion School of Medicine, Texas Christian University, Fort Worth, Texas, USA
3Shahid Beheshti University of Medical Sciences, Tehran, Iran
4Islamic Azad University Tehran Medical Sciences

*Corresponding Author: Meisam Sargazi, Assistant Professor of Ophthalmology, Zahedan University of Medical Sciences, Zahedan, Iran.
Received: July 27, 2024; Published: September 04, 2024



Objective: To evaluate and compare the structural and functional outcomes of conventional and sutureless methods of trabeculectomy at 6-month follow-up.

Methods: Of the patients referred for trabeculectomy, 18 were selected (8 males and 10 females). Patients were randomly divided into two equal groups: conventional surgery and sutureless surgery. Bleb morphologic parameters were measured using anterior segment optical coherence tomography at 6 months follow-up. The obtained data were statistically analyzed by T-test and Chi-square using SPSS software.

Results: The mean postoperative morphological parameters including bleb height, width, and wall thickness were lower in the sutureless group while the difference was not statistically significant. Bleb wall pattern, reflectivity, and vascularity difference between the two groups were also not statistically significant. Furthermore, there was no statistically significant difference in intraocular pressure between the two groups.

Conclusion: No significant difference in bleb morphology parameters and intraocular pressure was observed between the two groups of conventional and sutureless methods at 6 months follow-up. A study with a longer follow-up and a higher statistical population is recommended.

Keywords: Trabeculectomy; Bleb; ASOCT; Glaucoma

  1. Kojima Sachi., et al. "Filtering blebs using 3-dimensional anterior-segment optical coherence tomography: a prospective investigation”. JAMA Ophthalmology2 (2015): 148-156.
  2. Kim Dong Myung., et al. "Comparison of localized retinal nerve fiber layer defects between a low-teen intraocular pressure group and a high-teen intraocular pressure group in normal-tension glaucoma patients”. Journal of Glaucoma3 (2007): 293-296.
  3. Kokubun Taiki., et al. "Quantification of the filtering bleb's structure with anterior segment optical coherence tomography”. Clinical and Experimental Ophthalmology6 (2016): 446-454.
  4. Oh Lawrence J., et al. "Comparison of bleb morphology between trabeculectomy and deep sclerectomy using a clinical grading scale and anterior segment optical coherence tomography”. Clinical and Experimental Ophthalmology7 (2017): 701-707.
  5. Yarmohammadi Adeleh., et al. "Relationship between optical coherence tomography angiography vessel density and severity of visual field loss in glaucoma”. Ophthalmology 12 (2016): 2498-2508.
  6. Suh Min Hee., et al. "Deep retinal layer microvasculature dropout detected by the optical coherence tomography angiography in glaucoma”. Ophthalmology12 (2016): 2509-2518.
  7. Lee Si Hyung., et al. "Vascular and metabolic comorbidities in open‐angle glaucoma with low‐and high‐teen intraocular pressure: a cross‐sectional study from south Korea”. Acta Ophthalmologica7 (2017): e564-e574.
  8. Wen Joanne C., et al. "Comparison of anterior segment optical coherence tomography bleb grading, moorfields bleb grading system, and intraocular pressure after trabeculectomy”. Journal of Glaucoma5 (2017): 403-408.
  9. Sacu Stefan., et al. "Correlation between the early morphological appearance of filtering blebs and outcome of trabeculectomy with mitomycin C”. Journal of Glaucoma5 (2003): 430-435.
  10. Güven Yılmaz Suzan., et al. "Evaluation of filtering bleb function after trabeculectomy with mitomycin-c using biomicroscopy, anterior segment optical coherence tomography and in vivo confocal microscopy”. Turkish Journal of Ophthalmology4 (2015): 132-137.
  11. Narita Akiko., et al. "Characteristics of successful filtering blebs at 1 year after trabeculectomy using swept-source three-dimensional anterior segment optical coherence tomography”. Japanese Journal of Ophthalmology3 (2017): 253-259.
  12. Choi Woo June., et al. "Optical coherence tomography based microangiography for quantitative monitoring of structural and vascular changes in a rat model of acute uveitis in vivo: A preliminary study”. Journal of Biomedical Optics1 (2015): 016015.

Meisam Sargazi., et al. "Conventional Trabeculectomy vs. Sutureless Trabeculectomy in Patients with Uncontrolled Glaucoma: Structural and Functional Outcomes." EC Ophthalmology 15.9 (2024): 01-11.