EC Ophthalmology

Mini Review Volume 14 Issue 4 - 2023

Association of Alzheimer’s Disease, Chronic Glaucoma and Age-Related Macular Degeneration

Alexandros Tsilis1* and Sygkliti-Henrietta Pelidou2

1Faculty of Medicine, University of Ioannina, Ioannina, Greece
2Department of Neurology, University of Ioannina School of Medicine, Ioannina, Greece

*Corresponding Author: Alexandros Tsilis, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Received: March 01, 2023; Published: March 20, 2023




Recent evidence has suggested a potential association between Alzheimer’s disease (AD), chronic glaucoma (CGL) and age-related macular degeneration (AMD). Although several lines of evidence indicate that CGL and AMD may be associated with AD due to common pathophysiological mechanisms including progressive neurodegeneration, characteristic amyloid-β (Aβ) deposits and chronic microvascular insults, there is still no definite answer. Therefore, we conducted a mini-review to describe the findings of the AD, CGL and AMD literature. Further research, including large and well-designed prospective studies with long follow-ups, is needed to clarify this association.

Keywords: Neurodegenerative Diseases; Alzheimer’s Disease; Chronic Glaucoma; Age-Related Macular Degeneration

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Alexandros Tsilis and Sygkliti-Henrietta Pelidou. Association of Alzheimer’s Disease, Chronic Glaucoma and Age-Related Macular Degeneration. EC Ophthalmology 14.4 (2023): 08-14.

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