EC Gynaecology

We report the case of a 43-year-old patient with a rare metastatic choriocarcinoma complicated by uterine rupture and hemoperitoneum. On admission, she presented with severe hypovolemic shock requiring urgent intervention. Laparotomy revealed massive hemoperitoneum with rupture of the uterine horn. A total abdominal hysterectomy was performed and histopathological evaluation confirmed the diagnosis of choriocarcinoma. Post-operative treatment included methotrexate + folinic acid chemotherapy, which showed a favorable response with a reduction in βHCG levels and regression of metastases. This case highlights the importance of increased clinical vigilance in gestational trophoblastic disease to prevent serious complications.

 Keywords: Choriocarcinoma; Uterine Rupture; Hemoperitoneum; Gestational Trophoblastic Disease; Chemotherapy

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