EC Gynaecology

Granulosa cell tumor (GCT) belongs to the group of sex cord-stromal tumors and represents approximately 2 - 5% of cases. GCTs are divided into two subtypes: the adult type, which accounts for 95% of all GCTs, and the juvenile type, accounting for the remaining 5%. The adult subtype most commonly occurs in patients between 50 and 54 years old, while the juvenile subtype usually develops before puberty.

The distinct feature of GCTs is their malignant potential, evidenced by long-term recurrences. Herein, we report a case of an adult-type GCT in a 62-year-old female patient, and provide a detailed analysis of its clinical presentation, diagnosis and treatment. The patient was successfully treated with primary debulking surgery and adjuvant chemotherapy.

The importance of an early diagnosis and long-term follow-up is emphasized, given the risk of recurrence. This case provides a comprehensive view of GCT management and highlights the need for a thorough evaluation and an interdisciplinary approach for an effective treatment of this uncommon ovarian neoplasm.

 Keywords: Granulosa Cell Tumor; Ovarian Cancer; Sex Cord-Stromal Tumor; Hyperestrogenism

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