EC Gynaecology

Case Report Volume 14 Issue 1 - 2025

Preoperative Diagnosis of Primary Fallopian Tube Cancers: A Challenging Situation

Abdeladim Ayadine*, Chaka Dembélé, Fatima El Mangoub, Saad Benali, Moulay Mehdi Elhassani and Jaouad Kouach

Department of Gynecology-Obstetrics, Mohammed V Military University Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco

*Corresponding Author: Abdeladim Ayadine, Department of Gynecology-Obstetrics, Mohammed V Military University Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Received: November 29, 2024; Published: December 17, 2024



Fallopian tubes have a low oncogenic potential, making primary fallopian tube cancers (PFTC) a rare entity. The prevailing histological type is serous adenocarcinomas (especially papillary serous).

They are often shadowed by ovarian cancers, and sometimes it's hard to tell the difference between the two entities. The diagnosis is chiefly made by ultrasounds eventually followed by MRI. The staging and management are identical to ovarian cancers.

We report the case of a giant PFTC mistook preoperatively for an ovarian cancer, diagnosed and treated at an early stage, with no sign of relapse after 15 months follow-up.

 Keywords: Fallopian Tube Cancer; Adenocarcinoma; Diagnosis; Treatment; Case Report

  1. Pectasides D., et al. “Fallopian tube carcinoma: a review”. Oncologist8 (2006): 902-912.
  2. Marina Stasenko., et al. “Fallopian tube carcinoma”. Journal of Oncology Practice 7 (2019): 375-382.
  3. MM Vaughan., et al. “Survival of patients with primary fallopian tube carcinoma”. International Journal of Gynecological Cancer 1 (1998): 16-22.
  4. HD Nelson., et al. “Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U.S. Preventive services task force recommendation”. Annals of Internal Medicine 4 (2014): 255-266.
  5. Baekelandt M., et al. “Carcinoma of the fallopian tube”. Cancer 10 (2000): 2076-2084.
  6. Ajithkumar TV., et al. “Primary fallopian tube carcinoma”. Obstetrical and Gynecological Survey 4 (2005): 247-252.
  7. Lin CK., et al. “Primary fallopian tube cancer may mimic endometrial malignancy”. Taiwanese Journal of Obstetrics and Gynecology2 (2008): 218-219.
  8. Rosenblatt KA., et al. “Incidence of malignant fallopian tube tumors”. Gynecologic Oncology 2 (1989): 236-239.
  9. Riska A., et al. “Sociodemographic determinants of incidence of primary fallopian tube carcinoma, Finland 1953-97”. International Journal of Cancer 5 (2003): 643-645.
  10. R I Demopoulos., et al. “Clues to the pathogenesis of fallopian tube carcinoma: a morphological and immunohistochemical case control study”. International Journal of Gynecological Pathology 2 (2001): 128-132.
  11. MD WA. “Fallopian Tube Carcinoma” (2024).
  12. Y-R Hsu., et al. “Preoperative diagnosis of fallopian tube carcinoma by transvaginal sonography, MRI and CA125”. Tzu Chi Medical Journal 4 (2010): 225-228.
  13. Lau HY., et al. “Primary fallopian tube carcinoma: a clinicopathologic analysis and literature review”. Journal of the Chinese Medical Association10 (2013): 583-587.
  14. David W Kindelberger., et al. “Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship”. American Journal of Surgical Pathology 2 (2007): 161-169.
  15. Kurjak A., et al. “Preoperative diagnosis of primary fallopian tube carcinoma”. Gynecologic Oncology1 (1998): 29-34.
  16. Patlas M., et al. “Sonographic diagnosis of primary malignant tumors of the fallopian tube”. Ultrasound Quarterly 2 (2004): 59-64.
  17. Ko ML., et al. “Sonographic appearance of fallopian tube carcinoma”. Journal of Clinical Ultrasound 7 (2005): 372-374.
  18. Ghattamaneni S., et al. “Discriminative MRI features of fallopian tube masses”. Clinical Radiology 8 (2009): 815-831.
  19. Davies AP., et al. “Raised serum CA 125 preceding the diagnosis of carcinoma of the fallopian tube: two case reports”. British Journal of Obstetrics and Gynaecology 6 (1991): 602-603.
  20. Chi DS., et al. “A contemporary analysis of the ability of preoperative serum CA-125 to predict primary cytoreductive outcome in patients with advanced ovarian, tubal and peritoneal carcinoma”. Gynecologic Oncology 1 (2009): 6-10.
  21. C Kosary EL. “Trimble treatment and survival for women with fallopian tube carcinoma: a population-based study”. Gynecologic Oncology 2 (2002): 190-191.
  22. Bolze PA., et al. “Chirurgie des stades précoces des cancers ovariens. Recommandations françaises communes du CNGOF, FRANCOGYN, SFOG, GINECO-ARCAGY et labellisées INCa”. Gynécologie Obstétrique Fertilité and Sénologie 2 (2019): 168-179.
  23. De La Motte Rouge T., et al. “Traitements médicaux des cancers de l’ovaire lors de la prise en charge initiale. Recommandations de Pratique Clinique communes de FRANCOGYN, CNGOF, SFOG et ARCAGY-GINECO, labélisées par l’INCa”. Gynécologie Obstétrique Fertilité and Sénologie 2 (2019): 222-237.
  24. Sun M., et al. “Unexpected primary fallopian tube carcinoma during gynecological operations: Clinicopathological and prognostic factors analyses of 67 cases”. Taiwanese Journal of Obstetrics and Gynecology 58 (2019): 626-632.
  25. Wethington SL., et al. “Improved survival for fallopian tube cancer: a comparison of clinical characteristics and outcome for primary fallopian tube and ovarian cancer”. Cancer 12 (2008): 3298-3306.
  26. Heintz AP., et al. “Carcinoma of the fallopian tube. FIGO 6th annual report on the results of treatment in gynecological cancer”. International Journal of Gynecology and Obstetrics 1 (2006): 145-160.
  27. Gadducci A., et al. “Analysis of treatment failures and survival of patients with fallopian tube carcinoma: a cooperation task force (CTF) study”. Gynecologic Oncology2 (2001): 150-159.

Abdeladim Ayadine., et al. "Preoperative Diagnosis of Primary Fallopian Tube Cancers: A Challenging Situation". EC Gynaecology 14.1 (2025): 01-05.