EC Gynaecology

Research Article Volume 12 Issue 4 - 2023

Ovarian Hyperstimulation Syndrome and Pregnancy Outcome

Mahbod Kaveh1, Fateme Davari Tanha2*, Ensieh Shahrokhe Tehraninejad3 and Aida Cheraghi3

1Department of Neonatology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran

2Department of Obstetrics and Gynecology and Reproductive Endocrinology, Women Hospital, Tehran University of Medical Sciences, Tehran, Iran

3Department of Obstetrics and Gynecology and Reproductive Endocrinology, Vali-e-Asr Hospital, Valiasr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran

*Corresponding Author: Fateme Davari Tanha, Professor of Obstetrics and Gynecology, Reproductive Endocrinologist, Women’s Hospital of Tehran University of Medical Sciences, Valiasr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Received: January 24, 2023; Published: March 06, 2023



Objective: To compare pregnancy outcome in IVF pregnant women with and without ovarian hyperstimulation syndrome.

Methods: One hundred and forty pregnant women after IVF were recruited in this case control study. Seventy patients in case group with OHSS and seventy patients in control group without OHSS who referred to two referral university based hospital between January 2009 - September 2014 were evaluated. Obstetrics outcome like abortion, pregnancy induced hypertension, gestational diabetes and preterm labor, LBW and multiple pregnancies were evaluated.

Results: The case group were younger than control group (P = 0.001). BMI was similar in both groups. Primary infertility in case group was 40% versus 70% in control group (p = 0.02). Male factor infertility was the most common cause in both group (44% in case group and 51.4% in control, p = 0.495). 30% of patients in the case group had PCOS versus 25% in control group. Early OHSS was more common than late OHSS (84.3% versus 14.3%). PIH, LBW, multiple gestation, GDM and abortion was the same in both group but preterm labor was higher in OHSS group.

Conclusion: It seems that preterm labor was more common in the OHSS group (p = 0.05) but other pregnancy complications like pregnancy loss, pregnancy induced hypertension and gestational diabetes or low birth weight were similar in pregnant patients with and without OHSS.

Keywords: OHSS; PIH; GDM; Infertility; Multiple Pregnancy

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Fateme Davari Tanha., et al. Ovarian Hyperstimulation Syndrome and Pregnancy Outcome. EC Gynaecology 12.4 (2023): 05-10.