EC Gynaecology

Literature Review Volume 12 Issue 10 - 2023

Metastases in the Brain of Tumors of the Female Reproductive System: A Review of the Literature

Sevyan NV1,2*, Bekyashev AKh1, Prozorenko EV1,2, Naskhletashvili DR1, Aleshin VA1, Mitrofanov AA1, Moskvina EA1, Gasparyan TG1, Belov DM1 and Kirsanov VYu2

1Federal State Budgetary Institution “N. N.Blokhin National Medical Research Center of Oncology” of the Ministry of Healthcare of the Russian Federation, Moscow, Russia

2Federal State Autonomous Educational Institution of Higher Education “I. M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation (Sechenov University), Moscow, Russia

*Corresponding Author: Sevyan NV, Federal State Budgetary Institution “N. N.Blokhin National Medical Research Center of Oncology” of the Ministry of Healthcare of the Russian Federation and Federal State Autonomous Educational Institution of Higher Education “I. M. Sechenov First Moscow State Medical University” of the Ministry of Healthcare of the Russian Federation (Sechenov University), Moscow, Russia.
Received: August 28, 2023; Published: September 21, 2023




Introduction

The article presents a modern view on the treatment problem of patients with intracranial metastases of malignant tumors of the female reproductive system. The author presents their own experience in patients’ treatment with ovarian cancer (OC), cervical cancer (CC) and endometrial cancer (EC) with brain metastases.

Tumors of the female reproductive system metastasis to the brain is rare and studied pathology. Problems of their diagnosis and treatment remain to be solved. The paper details the clinical picture, X-ray, morphological diagnosis and treatment of patients with intracranial metastases tumors of the female reproductive system.

 Keywords: Metastases; Tumors; Brain; Cancer; Uterus; Central Nervous System; Reproductive System; Survival Rate; Oncology

  1. Adamyan LV and Aznaurova YaB. “Endometriosis and Cancer: a comparative characteristic and new perspectives of treatment and prevention”. Gynecology, Obstetrics and Perinatology3 (2020): 95-99.
  2. Safonova MA., et al. “Female reproductive organs lesion in the structure of multiple primary malignant neoplasms”. Gynecology, Obstetrics and Perinatology3 (2016): 48-53.
  3. Davydov AI., et al. “On markers of early detection of endometriosis-associated ovarian tumours”. Voprosy Ginekologii, Akusherstva i Perinatologii. (Gynecology, Obstetrics and Perinatology) 4 (2019): 133-137.
  4. Pakneshan S., et al. “Brain metastasis from ovarian cancer: a systematic review”. The Journal of Neuro-Oncology 1 (2014): 1-6.
  5. Nayak L., et al. “Epidemiology of Brain Metastases”. Current Oncology Reports 14 (2012): 48-54.
  6. Cormio G., et al. “Distant metastases in ovarian carcinoma”. The International Journal of Gynecological Cancer 13 (2003): 125-129.
  7. Tay SK and Rajesh H. “Brain metastases from epithelial ovarian cancer”. The International Journal of Gynecological Cancer 5 (2005): 824-829.
  8. Wang N., et al. Leptomeningeal metastasis from systemic cancer: Review and update on management 124 (2018): 21-35.
  9. Chamberlain MC. “Neoplastic meningitis”. Journal of Clinical Oncology (2005): 3605-3613.
  10. Lassman AB and DeAngelis LM. “Brain metastases”. Neurologic Clinics 21 (2003): 21-23.
  11. Nayak L., et al. “Epidemiology of brain metastases”. Current Oncology Reports 14 (2012): 48-54.
  12. Gavrilovic IT and Posner JB. “Brain metastases: epidemiology and pathophysiology”. Journal of Neuro-Oncology 75 (2005): 5.
  13. Klos KJ and O'Neill BP. “Brain metastases”. The Neurologist1 (2004): 31-46.
  14. Mariani A., et al. “Hematogenous Dis-semination in Corpus uteri Cancer”. Gynecologic Oncology2 (2001): 233-238.
  15. Anupol N., et al. “Evaluation of prognostic factors and treatment modalities in ovarian cancer patients with brain metastases”. Gynecologic Oncology 85 (2002): 487-492.
  16. Chura JC., et al. “Brain metastasis from cervical carcinoma”. The International Journal of Gynecological Cancer 17 (2007): 141-146.
  17. Batson OV. “The role of the vertebral veins in metastatic processes”. Annals of Internal Medicine 16 (1942): 38-45.
  18. Brown PD., et al. “Stereotactic radiosurgery for patients with “radioresistant” brain metastases”. Neurosurgery 51 (2002): 656-665.
  19. Uccellaa S., et al. “Primary brain metastases of endometrial cancer: A report of 18 cases and review of the literature”. Gynecologic Oncology1 (2016): 70-75.
  20. Cohen ZR., et al. “Brain Metastases in Patients with Ovarian Carcinoma: Prognostic Factors and Outcome”. Journal of Neuro-Oncology3 (2008): 313-325.
  21. Lee YK., et al. “Gamma knife radiosurgery as an optimal treatment modality for brain metastases from epithelial ovarian cancer”. Gynecologic Oncology 108 (2008): 505-509.
  22. Gadducci A., et al. “The management of patients with uterine sarcoma: a debated clinical challenge”. Critical Reviews in Oncology/Hematology2 (2008): 129-142.
  23. Zaytsev AM., et al. “The possibilities of treatment of patients with malignant neoplasms of the female reproductive system with metastatic brain lesion”. Issledovaniâ i Praktika v Medicine. (Research’n Practical Medicine Journal)3 (2016): 17-29.
  24. Marchetti C., et al. “Brain metastases in patients with EOC: Clinico-pathological and prognostic factors. A multicentric retrospective analysis from the MITO group (MITO 19)”. Gynecologic Oncology 143 (2016): 532-538.
  25. Kwon JW., et al. “Treatment results and prognostic factors of brain metastases from ovarian cancer: A single institutional experience of 56 patients”. The International Journal of Gynecological Cancer 28 (2018): 1631-1638.
  26. Sevyan NV., et al. “Brain metastases from gynecological cancers”. Voprosy Ginekologii, Akusherstva i Perinatologii. (Gynecology, Obstetrics and Perinatology)4 (2020): 172-177.

Sevyan NV., et al. Metastases in the Brain of Tumors of the Female Reproductive System: A Review of the Literature. EC Gynaecology 12.10 (2023): 01-04.

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