Case Report Volume 14 Issue 9 - 2025

Gilbert Syndrome’s Impact on Pregnancy: A Case Report

Reda RH Youssef1, Manal Shaker Taha2*, Ahmed Sabry1, Gamal Sayed Ahmed3, Ahmed H Abdelmonem1, Moayyad Younis3 and Amal Al Obaidly1

1Department of Clinical Imaging, Hamad Medical Corporation, Doha, Qatar

2Glangwili General Hospital, Carmaethen, United Kingdom

3Department of Obstetrics and Gynecology, Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, Qatar

*Corresponding Author: Manal Shaker Taha, Glangwili General Hospital, Carmaethen, United Kingdom.
Received: August 07, 2025; Published: August 30, 2025



Gilbert syndrome is a hereditary disorder of liver metabolism characterized by mild elevated unconjugated hyperbilirubinemia. We present a case report of a 29-year-old pregnant woman with a known diagnosis of Gilbert syndrome since childhood. She had a previous history of a child born by cesarean section with biliary atresia and gallbladder agenesis, requiring a liver transplant at 9 months.

During her current pregnancy, she was found to have elevated indirect bilirubin and hepatosplenomegaly and subsequently underwent an elective cesarean section at 39 weeks. The neonate did not develop neonatal hyperbilirubinemia, and both mother and baby remained healthy in postnatal follow-ups.

This case is unique due to its presentation and differing pregnancy outcomes, emphasizing the importance of accurate diagnosis and careful follow-up of pregnant patients with Gilbert syndrome.

 Keywords: Gilbert Syndrome; Pregnancy; Hyperbilirubinemia; Biliary Atresia; Gallbladder Agenesis

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Manal Shaker Taha., et al. “Gilbert Syndrome’s Impact on Pregnancy: A Case Report”. EC Gynaecology  14.9 (2025): 01-05.