EC Gynaecology

Chorangioma is a nontrophoblastic benign placenta tumor. It can be characterized by its size clinically; Many pregnancies are accompanied by small chorangioma; however, large chorangioma happens rarely (1:50,000), and it is more likely to occur in women over 30, first pregnancies, and diabetics. A 40-year-old diabetic mother, second gravida with a history of one abortion, was admitted to the hospital due to polyhydramnios. At the 19th week of gestation, we observed multilocular cystic at the edge of the placenta measuring 33*39 according to color doppler imaging. Also, we saw the fetal stomach a little prominent with a double bubble. Sonography done in the 25^th week revealed a slight polyhydramnios. The stomach was entirely prominent with a double bubble. An avascular multilocular cystic at the superior edge of the placenta measured 48*63 mm; at the 35^th week of gestation, an avascular solid cystic area measuring 69*78 with bulging to the amnion confirmed the placental chorioangioma on the 39^th week's patients underwent cesarian section. The placenta was fundal. The fetus and placenta weighed 3618g, which we had a healthy 3100g healthy boy, and a multilocular cystic weighing 518g binded to the placenta.

Keywords: Giant Placental Chorioangioma; Causing a Double Bubble; Diabetic Mother: Case Report

1. Guschmann M., et al. “Chorioangioma–new insights into a well-known problem I. Results of a Clinical and Morphological Study of 136 cases” (2003).
2. Lifschitz-Mercer B., et al. “Chorangioma. A cytoskeletal profile”. International Journal of Gynecological Pathology4 (1989): 349-356.
3. Liang S., et al. “Chorioangioma of the placenta: an ultrasonic study: Case report”. BJOG: An International Journal of Obstetrics and Gynaecology 6 (1982):480-482.
4. Fan M and Skupski DW. “Placental chorioangioma: literature review”. Journal of Perinatal Medicine 3 (2014): 273-279.
5. Ogino S and Redline RW. “Villous capillary lesions of the placenta: distinctions between chorangioma, chorangiomatosis, and chorangiosis”. Human Pathology 8 (2000): 945-954.
6. Ruman U., et al. “Placental chorioangioma: a case report”. BIRDEM Medical Journal 2 (2012): 113-115.
7. Jaiman S., et al. “Chorangioendothelioma of the placenta: a myth or reality?” Pediatric and Developmental Pathology 5 (2015): 410-415.
8. Taylor WM. “The double bubble”. New Physician 12 (1963): 277-278.
9. Chapman S. “The double bubble”. British Journal of Hospital Medicine 5 (1991): 337-338.
10. Bezerra JA., et al. “A one-month-old infant who had a 'double bubble”. Hospital Practice 4 (1992): 255.
11. Zanardini C., et al. “Giant placental chorioangioma: natural history and pregnancy outcome”. Ultrasound in Obstetrics and Gynecology: The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology 3 (2010): 332-336.
12. Bashiri A., et al. “Twelve cases of placental chorioangioma”. Archives of Gynecology and Obstetrics 1 (2002): 53-55.
13. Ghosh B and Byrd L. “Placental chorioangioma-an unusual cause of acute polyhydramnios with an isolated rise in maternal serum ALT: a clinical marker of disease and/or risk?” Journal of Obstetrics and Gynaecology: The Journal of the Institute of Obstetrics and Gynaecology 7 (2011): 663-664.
14. Willis C., et al. “Placental chorioangioma associated with polyhydramnios and hydrops fetalis”. BMJ Case Reports 1 (2019).
15. Barros A., et al. “Giant placental chorioangioma: a rare cause of fetal hydrops”. BMJ Case Reports (2011).
16. Kodandapani S., et al. “Chorioangioma of placenta: a rare placental cause for adverse fetal outcome”. Case Reports in Obstetrics and Gynecology (2012): 913878.
17. Guschmann M., et al. “Chorioangiomas – new insights into a well-known problem II”. An immuno-histochemical investigation of 136 cases 31.2 (2003): 170-175.