1Department of Obstetrics and Gynecology, College of Medicine, Jouf University, Sakaka, Kingdom of Saudi Arabia
2College of Medicine, Umm Al Qura University, Makkah, Kingdom of Saudi Arabia
3Faculty of Medicine, Tanta University, Tanta, Egypt
4College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia
5College of Medicine, King Faisal University, Kingdom of Saudi Arabia
6College of Medicine, King Abdulaziz University, Kingdom of Saudi Arabia
7College of Medicine, Jazan University, Kingdom of Saudi Arabia
8King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia
9Department of Obstetrics and Gynecology, College of Medicine, Umm AlQura University, Makkah, Saudi Arabia
10Obstetrics and Gynecology Department, College of Medicine, King Khalid University, Saudi Arabia
11Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Objective: This study's objective was to evaluate the awareness of Saudi women concerning the indications for the usage of Metformin in managing PCOS. It is the first-line treatment for managing insulin resistance-associated PCOS. Its underutilization stems from a lack of awareness among patients.
Methods: This cross-sectional study included women of reproductive age in Saudi Arabia. Copies of the electronic survey were distributed to the target population. The study was conducted over 2 months, November and December 2024.
Results: The study included 436 participants from Saudi Arabia. 38.8% were 20 - 30 years old. 82.1% recognized the importance of lifestyle changes for lowering insulin levels. While 36% were aware of metformin, 47.9% had not heard of it. 49.7% agreed that metformin might lower the chance of type 2 diabetes in women with PCOS, and 54.3% believed that it could help maintain regular menstrual cycles. Among the participants, 14.9% reported not using metformin, citing forgetfulness, side effects, and financial issues as barriers.
Conclusion: The majority of women had limited knowledge and understanding of this treatment. While most women with PCOS were aware of metformin as a medication, they lacked detailed information about its specific indications and benefits for managing PCOS. Many women did not know that metformin could help regulate menstrual cycles, improve insulin resistance, and potentially assist with weight management, which are key treatment goals for PCOS.
Keywords: Metformin; Polycystic ovarian syndrome; PCOS; Women; Saudi Arabia
Amany A Makroum., et al. "Awareness of Saudi Women on Metformin Indications for Polycystic Ovary Syndrome (PCOS)". EC Gynaecology 14.6 (2025): 01-11.
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