EC Gynaecology

Maternal anemia is a common complication of pregnancy, associated with significant adverse outcomes for both mothers and their infants. While iron deficiency is the primary cause, oxidative stress has emerged as a critical factor that exacerbates anemia. Antioxidants have gained attention for their potential to mitigate oxidative damage and improve maternal health. This narrative review explores the role of antioxidants in preventing maternal anemia during pregnancy. It examines the mechanisms by which oxidative stress contributes to anemia, the body's antioxidant defense systems, the types of antioxidants available, and the clinical evidence supporting their supplementation. Antioxidant supplementation may serve as a beneficial strategy for preventing maternal anemia, enhancing iron metabolism, and supporting overall maternal health. Although current evidence is promising, further research is necessary to determine the most effective antioxidants, their optimal dosages, and specific recommendations for clinical practice.

 Keywords: Maternal Anemia; Antioxidants; Pregnancy; Oxidative Stress; Nutritional Supplementation

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